Red Sox vs. Astros ALCS Game 1 Pick

Red Sox vs. Astros, 10/15/21 ALCS Game 1 Betting Predictions

Game 1 of the ALCS is set for 8:07 p.m. ET on Friday when the Astros host the Red Sox on FOX. With Chris Sale set to oppose Framber Valdez, which side has the edge tonight?

Game Snapshot

901 Boston Red Sox (+125) at 902 Houston Astros (-145); o/u 8.5

8:07 p.m. ET, Friday, October 15, 2021

Minute Maid Park, Houston, TX

Boston Red Sox DFS SPIN

Chris Sale will start Game 1 of the ALCS against the Astros. Sale will take the ball on Friday night for the opener of the best-of-seven series at Minute Maid Park in Houston. Nathan Eovaldi draws the starting assignment for Game 2 on Saturday afternoon. The 32-year-old lefty was shelled for five runs over one inning of work in his last postseason start against the Rays in Game 2 of the ALDS last week. He'll aim to rebound as the Red Sox attempt to make it back to the World Series for the second time in the last four years.

Houston Astros DFS Spin

Framber Valdez will start for the Astros in Game 1 of the ALCS on Friday night against the Red Sox. Luis Garcia is on tap for ALCS Game 2 with Lance McCullers (forearm) likely out for this round. Valdez registered a sharp 3.14 ERA with 125 strikeouts over 134 2/3 innings (22 starts) during the 2021 regular season, but he mostly struggled in his lone ALDS outing versus the White Sox last week.

Red Sox vs. Astros ALCS Betting Prediction

The Red Sox are 2-5 in their last seven games in Houston and are 2-5 in their last seven games versus the Astros overall. Boston is also 6-15 in its last 21 games as an underdog, is 2-5 in its last seven games versus a left-handed starter and is 5-13 in its last 18 games as a road underdog. The Astros, meanwhile, are 5-0 in their last five games as a favorite, are 5-1 in their last six games overall and are 4-0 in their last four home playoff games.

ALCS GAME 1 BETTING PREDICTION: HOUSTON ASTROS -145

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