Cardinals vs. Brewers, 9/22/21 MLB Predictions & Betting Odds

Cardinals vs. Brewers MLB Prediction

The red-hot Cardinals won their 10th straight game on Tuesday night when they pulled off the upset versus the Brewers. Will St. Louis make it three in a row versus its division rivals and 11 consecutive overall when the NL Central foes meet again at 7:40 p.m. ET?

Game Snapshot

905 St. Louis Cardinals (-105) at 906 Milwaukee Brewers (-115); o/u 9.5

7:40 p.m. ET, Wednesday, September 22, 2021

American Family Field, Milwaukee, WI

St. Louis Cardinals DFS Notes

Tommy Edman went 2-for-3 with an RBI single, a run scored, two stolen bases and a walk in Tuesday's win over the Brewers. A nice all-around game for Edman on the evening. He scored the game's first run, coming home on a sacrifice fly in the first inning. He later managed an eighth-inning RBI single to give the Cards a 2-0 lead. The Brewers would strike back with a run of their own in the bottom of the eighth inning, but a ninth-inning comeback was not ultimately to be for the home team. Overall this season, Edman is slashing .266/.313/.395 with 10 home runs, 50 RBI, 84 runs scored and 27 steals across 148 games played.

Milwaukee Brewers DFS Notes

Kolten Wong went 1-for-3 with a double and a walk in Tuesday's loss to the Cardinals. Wong was the only Brewers batter to pick up an extra-base hit in the 2-1 defeat. For the season as a whole, the 30-year-old second baseman is slashing a sturdy .275/.336/.452 with 13 home runs, 48 RBI, 64 runs scored and 10 steals across 107 games played.

Cardinals vs. Brewers MLB Betting Prediction

The Cardinals are now 12-1 in their last 13 games overall, are 7-0 in their last seven games versus a team with a winning record and have won six straight as an underdog. On the other side, the Brewers have dropped five of their last seven games overall and are 2-5 in their last seven games after scoring two runs or less in their previous contest.

MLB BETTING PREDICTION: ST. LOUIS CARDINALS -105