Astros vs. Padres, 9/5/21 MLB Predictions & Betting Odds

Astros vs. Padres MLB Prediction

The Astros and Padres split the first two games in their three-game set and will play the rubber match at 4:10 p.m. ET on Sunday. Which side will win the rubber match and the series today?

Game Snapshot

979 Houston Astros (-100) at 980 San Diego Padres (-108); o/u 8.5

4:10 p.m. ET, Sunday, September 5, 2021

Petco Park, San Diego, CA

Houston Astros DFS Notes

Yuli Gurriel went 2-for-3 with an RBI and a walk on Saturday against the Padres. In the top of the first, Gurriel knocked in the first run of the game on a 95.2 mph single. He also smacked a single to leadoff the top of the sixth and drew a walk in the top of the eighth. With tonight's effort, his OBP rose to .383 -- a career best mark. He was overlooked going into this season and over 439 at-bats, he has a .314/.383/.467 slash line with 13 home runs and a stolen base.

San Diego Padres DFS Notes

Manny Machado went 2-for-4 with a two-run home run, a double, two RBI, and a run scored in Saturday's victory over Houston. Machado got going as the game progressed tonight, as he hit his home run and double in the bottom of the seventh and bottom of the eighth, respectively. On top of this, he extended his hit streak to eight games with tonight's performance. Machado is slashing .276/.346/.493 with 24 home runs and 11 stolen bases over 475 at-bats in his age-29 campaign.

Astros vs. Padres MLB Betting Prediction

The Astros are just 1-4 in their last five games in San Diego and are 2-6 in their last eight games versus the Padres. They’re also 1-4 in their last five games as an underdog, are 1-4 in their last five games as a road underdog and are 3-7 in their last 10 interleague road games versus a right-handed starter. On the other side, the Padres are 22-8 in their last 30 interleague games as a favorite, are 23-8 in their last 31 interleague games versus a right-handed starter and are 11-5 in their last 16 interleague games versus a team with a winning record.

MLB BETTING PREDICTION: SAN DIEGO PADRES -108