Reds vs. Cardinals MLB Prediction

Reds vs. Cardinals, 4/24/21 MLB DFS Notes & Betting Predictions

The Cardinals held on to a 5-4 victory on Friday night against their NL Central rivals the Reds, but will Cincinnati take the second game of the series today at Busch Stadium? Wade Miley will oppose John Gant in the pitching matchup at 2:15 p.m. ET.

Game Snapshot

901 Cincinnati Reds (+111) at 902 St. Louis Cardinals (-121); o/u 8

2:15 p.m. ET, Saturday, April 24, 2021

VENUE: Busch Stadium, St. Louis, MO

Cincinnati Reds DFS SPIN

Nick Castellanos went 1-for-5 with a solo homer in Friday's loss to the Cardinals. Castellanos' sixth-inning blast was the only offense the Reds could manage against Kwang Hyun Kim. He actually came up with the chance to put the Reds ahead in the ninth, but he struck out against Alex Reyes. Cardinals fans probably enjoyed that one. Castellanos is now up to seven homers and 14 RBI on the year to go along with a strong .292/.320/.653 batting line.

St. Louis Cardinals DFS SPIN

Cardinals activated OF Tyler O'Neill from the 10-day injured list. O'Neill takes the roster spot vacated by John Nogowski, who has been placed on the injured list with a bone bruise in his left hand. The 25-year-old slugger appeared in just nine games, slashing .138/.167/.276 across 30 plate appearances, before hitting the injured list with a groin issue. He boasts enough raw over-the-fence pop to warrant consideration in deeper mixed leagues and NL-only formats, but he's struggled to get to that power in game action at the highest level over the past few seasons.

Reds vs. Cardinals Betting Prediction

The Reds are now just 4-9 in their last 13 games versus the Cardinals in St. Louis and have dropped five straight overall. They’re also 0-4 in their last four games as a road underdog, are 0-6 in their last six games versus an opponent with a losing record and are 1-4 in their last five road games when facing a right-handed starter. On the other side, the Cardinals have won four of their last five games as a favorite and are 5-2 in their last seven home games versus a left-handed starter.

MLB BETTING PREDICTION: ST. LOUIS CARDINALS -121

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