Blue Jays vs. Red Sox Prediction

Blue Jays vs. Red Sox, 4/20/22 MLB Betting Odds & Predictions

With the total sitting at 9.5 runs and the Red Sox listed as home underdogs on the money line, where’s the best betting value when it comes to Wednesday night’s AL East matchup between the Blue Jays and Boston at 7:10 p.m. ET?

Game Snapshot

921 Toronto Blue Jays (-138) at 922 Boston Red Sox (+115); o/u 9.5

7:10 p.m. ET, Wednesday, April 20, 2022

Fenway Park, Boston, MA

Toronto Blue Jays DFS SPIN

Zack Collins smacked a long solo home run in Tuesday's loss to the Red Sox. Collins greeted Nathan Eovaldi with a mammoth 432-foot blast to center field to lead off the second inning. It opened the scoring but wound up being the Blue Jays' lone tally of the night. The long ball was the second in three games for Collins, who is now 8-for-15 with two homers and two doubles in his last four contests. With Alejandro Kirk struggling, it's possible Collins is earning some starts in the designated hitter spot when Danny Jansen (oblique) returns, although a lot can happen between now and then.

Boston Red Sox DFS Spin

Trevor Story doubled in a run and drew a walk on Tuesday against the Blue Jays. Offense was difficult to come by in this one, with the Red Sox managing to squeak out a win on Story's RBI double and a Connor Wong sac fly. Things haven't totally clicked for Story yet, but he does have at least one hit in each of his six games since Opening Day.


The under is now 5-1 in the last six meetings between these two teams at Fenway Park following Boston’s 2-1 victory last night. The under is also 6-0 in the Blue Jays’ last six games as a road favorite, is 10-1 in their last 11 road games and is 4-1 in Toronto’s last five games overall. The under is also 4-0 in the Red Sox’ last four games when facing an opponent with a winning record and is 6-1 in their last seven games when playing the second game of a series.


MLB Headlines

MLB Predictions & Picks

Thumbnail Mets vs. Braves Prediction & Odds The New York Mets travel to Atlanta to take on the Braves Tuesday at 7:20 PM ET on TBS in the opening game of a three-game set.
Thumbnail Mariners vs. Padres Prediction The Mariners and Padres will square off at 9:40 p.m. ET on Tuesday night when Logan Gilbert opposes Joe Musgrove in the pitching matchup. With the Padres listed as a...
Thumbnail Cubs vs. Angels Prediction The Cubs are an underdog on Tuesday night against the Angels but they’ve had plenty of success versus L.A. in previous meetings. Will Chicago cash as an underdog tonight...
Thumbnail Giants vs. Rockies Prediction National League West rivals will square off at Coors Field when the Rockies host the Giants at 8:40 p.m. ET. Will San Francisco hit as road favorites or is there a...
Thumbnail Cardinals vs. Rangers Prediction Will the struggling Cardinals pick up a win in Texas on Tuesday night where they’ll visit the Rangers at 8:05 p.m. ET or will St. Louis suffer another ‘L’ when Matthew...