Indiana vs. Michigan State Prediction

Indiana Hoosiers vs. Michigan State Spartans, 9/25/19 Predictions & Odds

After a solid outing on the road last weekend, will No. 25 Michigan State be able to string together good showings when it hosts Indiana Saturday at 3:30PM ET?

Game Snapshot & Odds

153 Indiana vs. 154 Michigan State

Saturday, September 28, 2019

3:30PM ET – Spartan Stadium

TV: Big Ten Network

Compare odds and from multiple different online sportsbooks and shop for the best lines at our new NCAAF Odds & Betting Page.

Public Betting Trends

According to the latest oddsmakers, Michigan State is favored at home, as the Spartans are getting odds of -14.5 points against Indiana. The over/under total for the contest is listed at 45 points. The public betting currently has 51 percent going on Indiana as the underdog. This information is subject to change, however, so be sure to check out our NCAAF Public Betting Page for updated figures on the game.

Hoosiers struggle in Big Ten opener

Indiana is coming off a big 38-3 win over Connecticut last weekend, but the Hoosiers dropped a 51-10 decision at home to Ohio State two weeks ago. Indiana is 3-1 on the season, 0-1 in the Big Ten, 2-2 against the spread and 3-1 with the under.

IU has been respectable on defense for the season, allowing 19.5 points and 294.8 yards per game despite the awful showing against Ohio State. Offensively, Indiana is putting up 33.5 points and 429 yards per contest. Michael Penix Jr. is dealing with a hand injury that has forced him to miss the last two games. He has thrown for 523 yards and three touchdowns this year while Peyton Ramsey has thrown for 635 yards and five touchdowns. Peyton Hendershot is leading the receivers with 18 catches for 234 yards and three touchdowns while Stevie Scott III is the leading rusher with 215 yards and four scores.

Spartans bounce back

Michigan State bounced back from its 10-7 loss to Arizona State two weeks ago by picking up a 31-10 win at Northwestern last weekend. The Spartans are 3-1 on the year, 1-0 in the Big Ten, 2-2 against the spread and 2-2 with the over/under total.

MSU has a defense that is among the best in the nation, allowing just 11 points and 228.3 yards per game. Offensively, MSU is putting up 29.3 points and 406.5 yards per game this year. Brian Lewerke is leading the offense with 1,025 passing yards and seven touchdowns. Elijah Collins is the leading rusher with 357 yards and two scores while Darrell Stewart Jr. is the leading receiver with 30 catches for 439 yards and a score. Joe Bachie is leading the defense with 40 tackles, 1.5 sacks and 1 interception.

College Football Betting Trends


The Hoosiers are 2-9 against the spread in their last 11 road games and 4-12 ATS in their last 16 games on grass.

Michigan State

Michigan State is just 2-8 ATS in its last 10 home games and 4-10 ATS in their last 14 games on grass.


The Spartans have won and covered in five of their last six meetings with Indiana. However, MSU hasn’t been consistent on offense, especially with its blocking. Indiana has played well on defense aside from being beat down by Ohio State. However, MSU is not Ohio State. This is a big trap game for Michigan State. The Spartans are coming off a big road win and have Ohio State, Wisconsin and Penn State over the next three games. It would be easy for MSU to take its foot on the gas this week and try and stay healthy for the Buckeyes.

College Football Week 5 Prediction: Indiana +14.5


College Football Predictions

Thumbnail 2022 Heisman Trophy Odds A new college football season will be here in no time and since it’s hard to predict what will happen

NCAAF Headlines