Bills vs. Patriots, 12/28/20 NFL Week 16 Betting Predictions

Bills vs. Patriots MNF Prediction

Monday night will be the Patriots’ first game played while already eliminated from the playoffs since the 2000 season finale. Will they play like they have house money versus the Bills or will Buffalo cover the 7.5-point number in this AFC East clash?

Game Snapshot

481 Buffalo Bills (-7.5) at 482 New England Patriots (+7.5); o/u 47

8:15 p.m. ET, Monday, December 28, 2020

Gillette Stadium, Foxborough, MA

Buffalo Bills DFS Spin

Stefon Diggs (foot) is practicing in full for Week 16 against the Patriots. Diggs gave Bills fans and fantasy managers a fright when he came up limping late in last Saturday's blowout win over the Broncos, but it ended up being nothing more than a scare. The NFL's receptions leader will be ready to rock as the division-champion Bills look to put a symbolic bow on the AFC East with a victory over Bill Belichick's Patriots. Stephon Gilmore will not be a go, enhancing Diggs' top-five ranking.

New England Patriots DFS Spin

Cam Newton has five passing touchdowns in 13 games this season. Newton has thrown three touchdowns over his past six outings. It's bleak for the Patriots passing game -- and the offense in general -- as Joe Flacco has more touchdown tosses than Newton this season in just five games. What started out on a hopeful note for Newton and the Patriots has dissolved into a disaster; the team will miss the playoffs for the first time since 2008 after Week 15's loss to Miami. The veteran isn't playable outside of superflex formats in Week 16 against the Bills.

Bills vs. Patriots Betting Prediction

The underdog is 3-0-1 against the spread in the last four series meetings between these two teams, while the Bills are just 2-5-1 against the spread in their last eight games versus the Patriots. On the other side, the Patriots have been highly profitable as an underdog, posting a 38-18-3 record against the spread in their last 59 games catching points. They’re also a perfect 4-0 against the number in their last four games as a home dog.

MONDAY NIGHT FOOTBALL PREDICTION: NEW ENGLAND PATRIOTS +7.5