Green Bay Packers vs. San Francisco 49ers, 11/22/19 NFL Predictions & Odds

Packers vs. 49ers Total Prediction

The Sunday Night Football matchup this weekend is excellent, as the 8-2 Packers visit the 9-1 49ers at 8:20 p.m. ET. With the total jumping from 45.5 up to 47.5, is the over the best play for this matchup of NFC title contenders?

Game Snapshot

271 Green Bay Packers (+3) at 272 San Francisco 49ers (-3); O/U 47.5

8:20 p.m. ET, Sunday, November 22

Levi’s Stadium, Santa Clara, CA

Public Betting Trends

According to our NFL Football Public Betting Chart page, the Packers are receiving 57% of the betting tickets from online sportsbooks.

Green Bay Packers Fantasy Spin

Davante Adams (toe) wasn't listed on the Packers' final injury report. Adams trails only Tyreek Hill, Michael Thomas, Stefon Diggs and Amari Cooper in yards per route run this season (PFF). Aaron Rodgers' No. 1 WR has at least eight targets in five of his six games. Overall, only Robert Woods (71 targets) and Mike Williams (62) have more targets than Adams (57) without a receiving touchdown through 11 weeks. The likelihood of Adams being closer to full health after their Week 11 bye, the confirmation that he's been as efficient as ever on a per-route basis, along with the reality that the 49ers don't ask their CBs to travel with specific receivers means you can treat Adams as a top-five option at the position in this spot.

San Francisco 49ers Fantasy Spin

George Kittle (knee) is questionable for the 49ers' Week 12 matchup against the Packers. Ross Dwelley has posted 92% and 90% snap rates in two games with Kittle inactive. He hasn't cleared even 30 receiving yards in 21 career games, but obviously coach Kyle Shanahan trusts the undrafted second-year TE enough to feature him near the end zone. Treat Dwelley as a touchdown-dependent TE2 if Kittle remains sidelined. Obviously Kittle should be fired up as a high-end TE1 if active regardless of the matchup.

NFL Betting Trends

Green Bay

The under is 7-1 in the Packers’ last eight games after allowing more than 250 yards passing in their previous game.

San Francisco

The over is 5-1 in the 49ers’ last six games after accumulating more than 350 total yards in their previous game.

Prediction

The over is 7-2 in the last nine meetings between these two teams, is 20-8 in the Packers’ last 28 road games and is 20-7 in their last 27 games after allowing more than 350 total yards in their previous game. On the other side, the over is 4-0 in the Niners’ last four games overall, is 4-0 in their last four conference matchups and is 9-3 in their last 12 games versus an opponent with a winning record.

NFL Week 12 Prediction: Packers/49ers OVER 47.5