Panthers vs. 49ers Week 8 Prediction

Panthers vs. 49ers, 10/27/19 NFL Week 8 Betting Predictions

The 49ers will put their unbeaten record on the line Sunday when they host the Panthers at 4:05 p.m. ET. With San Francisco laying 5 points as a home favorite, is there value in a Carolina team that hasn’t lost since Kyle Allen took over for the injured Cam Newton?

Game Snapshot

269 Carolina Panthers (+5) at 270 San Francisco 49ers (-5); O/U 41

4:05 p.m. ET, Sunday, October 27, 2019

Levi’s Stadium, Santa Clara, California

Public Betting Trends

According to our NFL Football Public Betting Chart page, the Panthers are receiving 51% of the betting tickets from online sportsbooks.

Carolina Panthers Fantasy Spin

Cam Newton (foot) has yet to resume practicing. The Panthers have already announced Kyle Allen as their Week 8 starter, but they seemed to be holding out hope that Newton might be able to get some reps in. That did not happen on Wednesday or Thursday. It bodes poorly for Newton's odds of returning in Week 9, though that still can't be ruled out.

San Francisco 49ers Fantasy Spin

Marquise Goodwin (personal) is questionable for the 49ers' Week 8 matchup against the Panthers. Goodwin is off the fantasy radar if active, as Dante Pettis (92%) and Kendrick Bourne (89%) pulled away from the likes of Richie James (50%), Goodwin (11%) and Jordan Matthews (5%) with Deebo Samuel (knee) sidelined in Week 7. Bourne is probably the odd man out once Samuel returns, while coach Kyle Shanahan said recently-acquired WR Emmanuel Sanders is going to play "a lot."

NFL Betting Trends


The Panthers are 4-0 against the spread in their last four road games and have covered in four straight games overall.

San Francisco

The 49ers are just 8-17 against the spread in their last 25 home games and have failed to cover in 11 of their last 15 conference matchups.


Carolina is one of my favorite plays on Sunday. Why not take five points with a Panthers team that is unbeaten since Newton went out with an injury? Christian McCaffrey is a stud, Allen has kept the offense afloat without Newton and the Carolina secondary is outstanding. The Panthers are also 14-3 against the spread in their last 17 games versus the 49ers and are 9-1 against the number in their last 10 games in San Francisco. I love the value with the Panthers here.

NFL Week 8 Prediction: Carolina Panthers +5


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