Cardinals vs. 49ers TNF Pick

Will Cardinals vs. 49ers be a defensive struggle in Week 5 on Thursday?

Will the Thursday Night Football matchup between the Cardinals and 49ers be low-scoring for bettors at 8:25PM ET?

According to oddsmakers from online sports book BetDSI, the Cardinals are 4-point road favorites versus the 49ers after San Francisco opened as only a 2.5-point dog. As for the total, the number currently sits at 43.5 points after opening at 42.5.

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Arizona enters play having dropped three of its first four games to start the season. The Cardinals' latest loss came at a price, as Carson Palmer suffered a concussion in the team's 17-13 loss to the Rams. As of this writing, it's assumed that Drew Stanton will start for the Cardinals but nothing is official. The Cardinals are 1-3 straight up and 1-3 against the spread.

San Francisco also enters Week 5 coming off a loss and is also 1-3 to start the season. The Niners blew a 14-0 lead to the Cowboys in an eventual 24-17 defeat as a 1-point underdog last Sunday. Despite average play from quarterback Blaine Gabbert (16-of-23 for 196 yards with one touchdown and one interception), Chip Kelly maintains that he's not considering a change at signal-caller.

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OUR PICK: Whether it's Palmer or Stanton, this game should fall under on Thursday night. The under has cashed in nine of the Cardinals' last 12 games overall and is 4-0 in their last four games versus teams from inside their division. The under is also 8-1 in the Niners' last nine games played on Thursday, is 20-6 in their last 26 home games, and is 9-3 in their last 12 games versus divisional opponents. Expect a low-scoring affair in Santa Clara.



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