Last Updated on September 11, 2022 11:34 am by Anthony Rome
49ers vs. Bears Prediction & Odds
At least for now, the 49ers are handing the keys to the offense to Trey Lance, who will face the Bears at 1:00 p.m. ET on Sunday.
Even though Chicago isn’t projected to contend this season, is 6.5 too much to pass up on the home underdog in Week 1?
Game Matchup & Betting Odds
463 San Francisco 49ers (-6.5) at 464 Chicago Bears (+6.5); o/u 40.5
1:00 p.m. ET, Sunday, September 11, 2022
Solider Field, Chicago, IL
49ers vs. Bears Public Betting Information
Our NFL Public Betting Information page indicates that 65% of public bettors are currently backing the 49ers when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
San Francisco 49ers DFS Spin
ESPN’s Adam Schefter reports George Kittle (groin) is not expected to play Week 1 against the Bears. This is not a surprise considering Kittle sat out the entire week of practice after suffering a groin injury on Monday. Kittle managers should look to lower rostered options like Irv Smith on the waiver wire. Kittle should be considered truly questionable for Week 2.
Chicago Bears DFS Spin
Velus Jones (hamstring) is doubtful for Week 1 against the 49ers. Jones didn’t practice at all this week and missed a lot of time during training camp with an injury. He’s got a lot of ground to make up if he wants to become a contributor on offense as a rookie. Darnell Mooney, Byron Pringle, and Equanimeous St. Brown figures to be Justin Fields’ three-wide set Sunday.
49ers vs. Bears Betting Trends
Under is 7-1 in 49ers last 8 games overall
Under is 5-1 in 49ers last 6 road games
Under is 20-7 in Bears last 27 home games
49ers vs. Bears Prediction:
The road team is 5-1 against the spread in the last six meetings between these two teams, while the 49ers are a perfect 5-0 against the spread in their last five games dating back to last season. They’re also 4-0 against the number in their last four road games, are 5-0 at the betting window in their last five conference games and have covered in five of their last seven games as a favorite. The Bears, meanwhile, are just 3-9 ATS in their last 12 games overall and 1-5 against the number in their last six home games.
NFL WEEK 1 PREDICTION: SAN FRANCISCO 49ERS -6.5