Louisville vs. Indiana, 9/16/23 College Football Betting Odds, Prediction & Trends

Louisville vs. Indiana, 9/16/23 College Football Betting Odds, Prediction & Trends Louisville vs. Indiana, 9/16/23 College Football Betting Odds, Prediction & Trends

Last Updated on September 16, 2023 11:29 am by Anthony Rome

Louisville vs. Indiana Prediction

Louisville and Indiana will square off at Lucas Oil Stadium on Saturday afternoon at 12:00 p.m. ET. With the Hoosiers listed as 10-point underdogs and the total sitting at 50.5, what’s the smart bet when it comes to this ACC versus Big Ten matchup?

Game Matchup & Betting Odds

123 Louisville Cardinals (-10) at 124 Indiana Hoosiers (+10); o/u 50.5

12:00 p.m. ET, Saturday, September 16, 2023

Lucas Oil Stadium, Indianapolis, IN

Louisville vs. Indiana Public Betting Information

As of this writing, our CFB Public Betting page shows that 52% of bets are on Indiana. That said, this page is updated frequently so make sure that you click on the link provided so that you’re getting the most updated information.

Louisville Cardinals Game Notes

Jack Plummer completed 16-of-22 passes for 247 yards with one touchdown and two interceptions in Thursday’s 56-0 win over Murray State. The Cardinals easily handled Murray State as they put up 690 yards of total offense with almost a dead even split, 346-yards through the air and 344-yards on the ground. Plummer put up a solid yardage number passing after playing just two and a half quarters but was off the mark a few times including two interceptions to the far inferior Murray State defense.

Indiana Hoosiers Game Notes

Indiana’s head coach Tom Allen said Cam Camper (lower body) has “had a good week of practice” while preparing for Week 3, Zach Osterman of The Indianapolis Star reports. Little had been known about Camper’s injury status until Allen publicized some information about it during a press conference Thursday. The head coach did not confirm that his injured receiver will be available during Week 3. However, there is a chance Camper plays against Louisville on Saturday. More information should be known about his future availability when Indiana’s team releases its injury report then.

Louisville vs. Indiana Betting Trends

Louisville is 4-1 SU in its last 5 games

The total has gone UNDER in 5 of Louisville’s last 7 games

The total has gone OVER in 4 of Indiana’s last 6 games

Indiana is 7-17 ATS in its last 24 games

Louisville vs. Indiana Betting Prediction

I’m taking the points. Louisville has a good offense but the unit has struggled to convert third downs to start the season, whereas Indiana has been great on third downs. The Hoosiers struggled offensively against the Buckeyes in Week 1, but they held what should eventually be an explosive OSU offense somewhat in check. I don’t love Indiana’s offense but the defense will keep the Hooisers in the game and within the 10-point spread.

COLLEGE FOOTBALL WEEK 3 PREDICTION: INDIANA HOOSIERS +10