Last Updated on September 27, 2025 8:26 am by Anthony Rome
BYU at Colorado closes the Week 5 slate late Saturday night in Boulder (10:15 p.m. ET, ESPN). This BYU at Colorado preview compares opening odds vs. current odds, public betting splits, key injuries, weather, three sharp trends, and our expert pick with buy/sell points. For live context, hit the CFB public betting chart and check the College Football hub.
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Game Snapshot — BYU at Colorado
- Matchup: No. 25 BYU Cougars at Colorado Buffaloes
- Date/Time: Sat, Sept. 27, 2025, 10:15 p.m. ET
- TV: ESPN
- Venue: Folsom Field (Boulder, CO)
Opening Odds — BYU vs Colorado odds
- Spread: BYU −6.5
- Moneyline: BYU ~−245 / Colorado +190
- Total: 46.5
- Notes: Near-TD opener to BYU with a total set in the mid-40s.
Current Odds — BYU at Colorado (open → now)
- Spread: BYU −6.5 (−110) / Colorado +6.5 (−110)
- Moneyline: BYU −250 / Colorado +200
- Total: 50 (market range across books)
- Move note: Holding opener band; total toggling mid-40s.
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Public Money — Tickets %, Money %, Line Moves
- Tickets % (Spread): Majority leaning Colorado as a home dog.
- Money % (Spread): Larger wagers siding with BYU −6.5.
- Total Market: Split action; Over gaining interest when 47s appear.
Injuries & Weather
- BYU: OL rotation expected intact; RB usage worth confirming morning-of.
- Colorado: One DB questionable; QB/WR core in line to go.
- Weather: Clear, mid-60s, light wind — neutral scoring setup in Boulder.
Trends That Matter — BYU at Colorado
- BYU 6–2 ATS in last eight non-conference games.
- Colorado 5–1 ATS across the last six at Folsom Field.
- Unders are 7–3 in BYU’s last 10 road contests.
Expert Pick & Buy Points
Pick: BYU −6.5 — prefer laying under a TD; totals lean Under at the top of the range.
- Buy up to: −6.5 (−115 max)
- Sell down to: −7.5 (smaller stake if it gets there)
- Alt options: Under 47.5; Colorado +7.5 if the market pops the hook.
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