Cardinals vs Seahawks Picks – Anytime TD Parlay +775 Week 10

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SEATTLE, WA — The Seahawks return to Lumen Field with control of the division race in sight as Arizona arrives for a late-window Week 10 matchup. The board shows Seattle −6.5 (−120), with a total of 45 (−110/−110). Mooneylines near SEA −330 / ARI +265 respectively. With kickoff set for Sunday, 4:05 p.m. ET on FOX, our Cardinals vs Seahawks picks lean into early-quarter edges and a player-prop scoring angle that complements, not duplicates, the paired Odds article.

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Cardinals vs Seahawks Odds — Week 10

Team Spread Total ML
Arizona Cardinals +6.5 (−110) 45 (O −110 / U −110) +265
Seattle Seahawks −6.5 (−120) 45 (O −110 / U −110) −330

Cardinals vs Seahawks — Picks

Play 1: 1st Quarter Seahawks −2.5 (−115) — Seattle tends to script shot plays at home; crowd noise + short fields can push a quick margin without tying up the full-game number.

Play 2: 2nd Quarter Under 13.5 (−125) — After the opening volley, both offenses often throttle down; this isolates a slower middle frame and avoids duplicating the full-game Under from the Odds article.

Read our full Cardinals vs Seahawks Betting Preview here.

Who is The Public Betting – Week 10

Team % of Bets Open Current
Arizona Cardinals 33% +1.5 (−110) +6.5 (−110)
Seattle Seahawks 67% −1.5 (−110) −6.5 (−120)

Market Read: Roughly two-thirds of tickets back Seattle and the line has marched from −1.5 to −6.5. That’s market agreement, not a pure public fade; unless sharp buyback appears near +7, books look comfortable holding Seattle as a multi-score favorite at home.

Numbers update frequently — check the latest on the NFL public betting chart and learn usage basics in our public betting guide.

Cardinals vs Seahawks — Parlay +$775

Legs

  1. 1st Quarter Seahawks −2.5 (−115)
  2. 2nd Quarter Under 13.5 (−125)
  3. Anytime Touchdown — Kenneth Walker (+160)

Simplified payout (easy American-odds math):
Start $100 → win at −115 returns about $187 → roll on −125 returns about $337 → roll on +160 returns about $875 total (~$775 profit). Rounding varies by book; SGP rules may limit mixes.

Things to Know Before You Bet

  • Seattle’s home script often targets early explosives; Q1 spread isolates that advantage.
  • Both defenses can settle in after adjustments — hence the Q2 Under instead of a full-game total overlap.
  • Walker’s red-zone role makes him a reasonable TD leg at a plus price.

How to Watch Cardinals vs Seahawks

  • 📅 Date: Sunday, November 9, 2025
  • Time: 4:05 p.m. ET
  • 📺 TV: FOX
  • 🏟 Venue: Lumen Field — Seattle, WA

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