Week 2 delivers SEC fireworks as Ole Miss heads to Lexington to face Kentucky on Saturday, September 6. This Ole Miss at Kentucky game preview serves up everything from current odds and public betting action to the pivotal storylines shaping this high-profile matchup. The Rebels come rolled out offensively explosive, while Kentucky aims to leverage home-field grit and last year’s upset for another statement win.
Ole Miss at Kentucky Date/Time, Location & TV
- Date & Time: Saturday, September 6, 2025 – Kickoff at 3:30 p.m. ET (2:30 p.m. CT)
- Location: Kroger Field, Lexington, Kentucky
- TV/Streaming: ABC, also available via WatchESPN
Betting Odds (via Bovada)
Point Spread
- Ole Miss –10.5 | Kentucky +10.5
Moneyline
- Ole Miss –380 | Kentucky +300
Total (Over/Under)
- 50.5 — Over (–110) / Under (–110)
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Public Betting Snapshot
Public data shows strong backing for Ole Miss covering the double-digit spread, while totals action leans slightly toward the Over 50.5, driven by the Rebels’ offensive explosiveness.
See the latest breakdown here:
College Football Public Betting Chart
News, Notes & Storylines
- Ole Miss exploded offensively in its opener, racking up nearly 700 yards and 63 points. QB Austin Simmons now faces his first career road start, creating volatility.
- Kentucky leaned on its defense in a gritty Week 1 win, using Kroger Field’s home advantage to smother its opponent. Revenge is also in play—the Wildcats upset Ole Miss last season.
- Both teams bring SEC urgency to the table, making turnovers and red-zone efficiency the key swing factors.
Ole Miss at Kentucky Trends
- ATS (Against The Spread): The line opened around –9.5 and has climbed to –10.5 behind Ole Miss action.
- O/U (Totals): Bettors lean slightly toward the Over, reflecting confidence in Ole Miss’s tempo.
- Line Movement: Early sharp and public money has pushed the spread into double digits.
Previous Meetings (Recent Matchups)
- 2024: Kentucky upset Ole Miss 20–17 in Oxford.
- Both teams enter with split momentum, fueling another SEC rivalry showdown.
Final Thoughts
This matchup showcases SEC contrast—Ole Miss’s offensive firepower against Kentucky’s defensive toughness. The Rebels deserve favorite status, but the Wildcats’ home-field grit makes them a dangerous underdog.
Bet Considerations:
- Spread: Ole Miss –10.5 is steep; Kentucky +10.5 may be worth a look in Lexington.
- Total: The Over 50.5 has potential if Ole Miss dictates tempo, though Kentucky’s defense can cap scoring.
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Ole Miss at Kentucky Snapshot
| Detail | Info |
|---|---|
| Date & Time | Saturday, Sept 6, 2025 – 3:30 p.m. ET |
| Location | Kroger Field, Lexington, KY |
| TV | ABC / WatchESPN |
| Spread | Ole Miss –10.5 / Kentucky +10.5 |
| Moneyline | Ole Miss –380 / Kentucky +300 |
| Total (O/U) | 50.5 (O –110 / U –110) |
| Public Betting | Heavy backing for Ole Miss to cover |
| Series History | Kentucky upset Ole Miss in 2024 |
| Trends | Ole Miss pace drives Overs; line moved to –10.5 |