How to Watch Rams vs 49ers
📅 Sunday, November 9, 2025
⏰ 4:25 p.m. ET
📺 FOX
🏟 Levi’s Stadium (Santa Clara, CA)
Rams vs 49ers Odds — Current
| Team | Spread | Total | Moneyline |
|---|---|---|---|
| Los Angeles Rams | –5.5 (-110) | 49.5 (O –105) | –235 |
| San Francisco 49ers | +5.5 (–110) | 49.5 (U –115) | +195 |
Where the Game Will Be Won
The Rams’ offensive rhythm has improved behind Matt Stafford’s quicker reads and a balanced script. San Francisco relies on gap-sound defense and a steady run mix to protect its own QB from obvious pass situations. For Rams vs 49ers predictions, the key is which front four wins early—Los Angeles has generated pressures on 36% of dropbacks the past three weeks while San Francisco sits top five in EPA per rush. Whichever team controls tempo will set the total tone as well.
Rams vs 49ers — Who Is the Public Betting?
| Team | % of Bets | Open | Current |
|---|---|---|---|
| Los Angeles Rams | 49% | +1.5 (–110) | –5.5 (–110) |
| San Francisco 49ers | 51% | –1.5 (–110) | +5.5 (–110) |
Market Read: The sharp move from San Francisco favored to Los Angeles –5.5 shows pro support for the Rams even without public consensus. If the number creeps toward –6, expect buy-back on the home side. Numbers update frequently — check the latest on the NFL public betting chart and learn usage basics in our public betting guide.
Rams vs 49ers Prediction & Expert Pick
The Rams have been the more consistent scoring unit and own edges in red-zone execution and pressure rate. San Francisco can hang early with ball-control runs, but sustaining drives against this defensive front remains tough. Prediction: Rams –5.5 (EVEN). Lean: Under 49.5 (–115).
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