2014 NFL on FOX Game of the Week Odds & Spread: 49ers vs. Cardinals

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49ers vs. Cardinals Odds

GLENDALE, AZ (The Spread) – Two talented NFC West rivals meet up on Sunday afternoon when the Arizona Cardinals host the San Francisco 49ers at 4:05PM ET on FOX.

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San Francisco is 1-1 on the season, 1-0 on the road and 1-1 against the spread. Arizona is 2-0 on the year, 1-0 at home and 1-1 against the spread. The 49ers have won four straight meetings with the Cardinals.

Trends show that the 49ers are 9-2 against the spread in their last 11 against the Cardinals and 7-1 ATS in their last 8 trips to Arizona. These two have hit the over in 4 of their last 5 meetings.

According to oddsmakers from BetDSI, San Francisco is the favorite on the road, as the 49ers are getting odds of -3 points against the Cardinals. The over/under total for the game has been set at 42 points (View Matchup). The opening odds for this game had the 49ers favored by 2.5 points. The spread held there most of the week before moving to 3 last night. The over/under total hasn’t changed since opening at 42 points.

Arizona is off to a 2-0 start thanks to a 25-14 win over the Giants on the road last week. The Cardinals won last week’s game without Carson Palmer, who was dealing with a shoulder injury. He is not expected to play this week either, which means Drew Stanton will start again. Stanton was 14 of 29 passing last week for 167 yards. Andre Ellington rushed for 91 yards while Jonathan Dwyer added 31 yards. Dwyer has since been barred from the team following a domestic abuse incident. Calais Campbell led the Arizona defense last Sunday with 10 tackles, one sack and three tackles for loss.

San Francisco is coming off a surprising 28-20 loss at home to the Chicago Bears. San Francisco jumped out to a 17-0 lead in the first half, then fell apart. The 49ers had four turnovers in the game, which allowed Chicago to win with only 216 yards of offense. Colin Kaepernick was 21 of 34 passing for 248 yards and one touchdown, but was responsible for all four turnovers. Michael Crabtree had seven receptions for 82 yards to lead the offense while Patrick Willis had a team-high eight tackles.

Bet on NFL Week 3 Odds

In terms of Injuries, Arizona linebacker John Abraham (concussion) and defensive end Frostee Rucker (calf) are both questionable. San Francisco tight end Vernon Davis (ankle) and tackle Anthony Davis (hamstring) are both questionable as well.

The Public Bets for this game are currently backing the 49ers, as San Francisco is getting 69% of the wagers with odds of -3 points at Arizona on Sunday evening.

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