Giants vs Rams Prediction and Best Bet for Monday Night September 21
The New York Giants carry a 1-0 record and a fast-starting young quarterback across the country for Monday…
NFL Betting Analysis & Predictions
The newest NFL predictions and daily best bets from TheSpread — updated as games are added to the board. Browse the latest football analysis below, or jump to live numbers and betting trends:
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Giants vs Rams Odds: Spread & How to Watch Monday September 21
The Los Angeles Rams open SoFi Stadium for the 2026 season on Monday Night Football, and they do…
Colts vs Chiefs Prediction: Our Best Bets for Sunday Night September 20
The Indianapolis Colts visit the Kansas City Chiefs on Sunday Night Football, and the market has quietly drifted…
Raiders vs Chargers Prediction September 20: Will LA Right the Ship?
The Las Vegas Raiders visit SoFi Stadium on Sunday afternoon with a chance to do something they have…
Dolphins vs 49ers Prediction September 20: Can San Fran Cover 2 TD’s?
The San Francisco 49ers open their home schedule as one of the heaviest favorites on the Week 2…
Commanders vs Cowboys Prediction September 20: Who Leaves 0-2?
Two NFC East teams open Week 2 with the same record and a similar list of problems. The…
Seahawks vs Cardinals Prediction September 20: Seattle the Best Bet?
The Seattle Seahawks visit the Arizona Cardinals on Sunday, September 20, 2026, and the betting market has quietly…
Jaguars vs Broncos Prediction September 20: Is Denver the Best Bet?
The Jacksonville Jaguars carry a nine-game regular-season winning streak into Denver on Sunday afternoon. The Broncos, meanwhile, are…
Browns vs Buccaneers Prediction September 20: Buy the Half Point?
Two teams that expected more from Week 1 meet in Tampa on Sunday afternoon, and the market is…
Bengals vs Texans Prediction September 20: Easy Cover for Houston at Home?
The Cincinnati Bengals arrive in Houston at 1-0 and the Houston Texans open their home schedule at 0-1,…