Number 2 Duke heads to South Carolina to face unranked Clemson on Saturday night. The game is at 6:30 PM ET on ESPN. Can Clemson cover the 7-point spread as home underdogs? Keep reading for our Duke vs. Clemson prediction.
The Duke Blue Devils are 20-2 straight up in the regular season this year. They are 14-8 ATS this season.
The Clemson Tigers are 18-5 straight up in the regular season this year. They are 13-10 ATS this season.
Duke vs. Clemson Matchup & Betting Odds
763 Duke Blue Devils (-7) at 764 Clemson Tigers (+7); o/u 134.5
6:30 p.m. ET, Saturday, February 8, 2025
Littlejohn Coliseum, Clemson, SC
TV: ESPN
Duke vs. Clemson Public Betting Information
Our CBB Public Betting Information page indicates that 54% of public bettors are currently backing Clemson when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
Duke Blue Devils Game Notes
Blue Devils forward Mason Gillis is questionable to play against Clemson on Saturday. He’s dealing with an illness. Gillis is averaging 4.8 points per game in 14.4 minutes per contest this season.
Duke guard Tyrese Proctor was excellent in his team’s 83-54 blowout win over Syracuse on Wednesday night. The 6’6” junior put up 16 points, 2 rebounds, 2 assists, and 2 made free throws in 28 minutes. Proctor shot 5 of 12 from the field and 4 of 10 from long distance in the victory.
Clemson Tigers Game Notes
Tigers guard Del Jones is questionable for Saturday’s game with an ankle injury. Jones is averaging 4.1 points per game in 11.6 minutes per contest this season.
Clemson forward Ian Schieffelin had a nice game in his team’s 89-86 triple overtime loss to Georgia Tech on Tuesday night. In that contest, the 6’8” senior recorded 23 points, 8 rebounds, an assist, and 3 blocks in 42 minutes of game action. Schieffelin shot 6 of 10 from the field, 2 of 4 from beyond the arc, and 9 of 10 from the charity stripe in the defeat.
Duke vs. Clemson CBB Betting Trends
Duke is 5-1 ATS as a road favorite this season.
The Blue Devils are 6-3 ATS in their last 9 games overall.
The under is 36-22 in Duke’s games since the start of last season.
Clemson is 51-55-2 ATS after a loss since the start of the 2015 season.
Duke vs. Clemson CBB Prediction:
This Duke team is an absolute juggernaut. The Blue Devils are the only team in the country this season that ranks in the top 4 nationally in adjusted offensive efficiency and adjusted defensive efficiency according to Kenpom.com.
Additionally, Duke’s average scoring margin of +20.7 points per game is the best figure in America in 2024-25. Duke is 12-0 straight up in ACC play and 7-0 straight up on the road this season. The Blue Devils have won 16 straight games outright, and they’ve won each of their past 3 games by 13 points or more.
Two months ago, Duke was favored by 8.5 points on the road against Louisville. Duke won that game 76-65 and covered the spread. I could definitely see the Blue Devils winning and covering on the road against Clemson in a similar situation this weekend. For all of those reasons, I’m laying the points with Duke in this one.