White Sox vs. Indians MLB Prediction

White Sox vs. Indians, 9/24/21 MLB Predictions & Betting Odds

After winning the American League Central yesterday, will the White Sox have enough left in the tank to knock off the Indians on Friday night when the division rivals meet at 7:10 p.m. ET?

Game Snapshot

921 Chicago White Sox (-135) at 922 Cleveland Indians (+115); o/u 8.5

7:10 p.m. ET, Friday, September 24, 2021

Progressive Field, Cleveland, OH

Chicago White Sox DFS Notes

Andrew Vaughn picked up a two-run single on Thursday in the second game of a doubleheader against the Indians. Vaughn came off the injured list before the second game of the twin-billing, and the rookie hitter delivered with a two-run single that gave the White Sox a 2-1 lead in the sixth. Vaughn has not shown much consistency in 2021 when healthy -- very few young hitters have -- but there have been some real flashes that suggest that he's going to be a strong fantasy option in the coming years.

Cleveland Indians DFS Notes

Oscar Mercado hit a walk-off two-run homer in the second game of a doubleheader Thursday against the White Sox to give Cleveland a 5-3 win. Mercado came up with two outs, and he swatted a two-run homer off Jose Ruiz to give Cleveland the win and a split of the doubleheader. The win doesn't mean much for Cleveland, as they were eliminated from the AL Central competition with the loss in the first game. Mercado has his sixth homer, but is still slashing .219/.298/.374 on the year.

White Sox vs. Indians MLB Betting Prediction

The White Sox are 3-7 in their last 10 games in Cleveland, are 2-5 in their last seven road games and are 2-5 in their last seven games when favored. The Sox are also just 1-4 in their last five games versus American League Central rivals and are 2-5 in their last seven games when facing a right-handed starter.

MLB BETTING PREDICTION: CLEVELAND INDIANS +115

Loading...

MLB Headlines

MLB Predictions & Picks

Thumbnail Red Sox vs. Astros ALCS Game 1 Pick Game 1 of the ALCS is set for 8:07 p.m. ET on Friday when the Astros host the Red Sox on FOX. With Chris Sale set to oppose Framber Valdez, which side has the edge...
Thumbnail Dodgers vs. Giants Game 5 Prediction It all comes down to Thursday night in San Francisco when the Giants host their bitter rivals the Dodgers for Game 5 of the NLDS at 9:07 p.m. ET. Which team will...
Thumbnail Giants vs. Dodgers Game 4 Prediction The Giants are on the verge of eliminating the Dodgers and punching their ticket to the NLCS following their 1-0 win in Game 3 of the NLDS on Monday night. Is San...
Thumbnail Brewers vs. Braves Game 4 Prediction The Braves can eliminate the Brewers in Game 4 of the NLDS at 5:15 p.m. ET on Tuesday. With Charlie Morton set to face the Brewers for a second time in this...
Thumbnail Astros vs. White Sox Game 4 Prediction The White Sox staved off elimination by breaking out the bats last night in their rout of the Astros in Game 3. Will Chicago now even its series with Houston...