Cardinals vs. Giants, 5/5/22 MLB Betting Odds & Predictions

Cardinals vs. Giants Prediction

A pair of playoff teams from a year ago will meet in San Francisco on Thursday night when the Giants host the Cardinals at 9:45 p.m. ET. The Cardinals have owned this matchup in previous seasons but will that be the case tonight?

Game Snapshot

959 St. Louis Cardinals (-115) at 960 San Francisco Giants (-105); o/u 7.5

9:45 p.m. ET, Wednesday, May 5, 2022

Oracle Park, San Francisco, CA

St. Louis Cardinals DFS SPIN

Nolan Arenado delivered a three-run homer and a two-run single Wednesday versus the Royals. Arenado's homer was his seventh in 23 games this year. He's tops in the NL with 23 RBI, placing him five behind his Player of the Month counterpart in the AL, Jose Ramirez.

San Francisco Giants DFS Spin

Brandon Crawford went 1-for-3 with a solo home run in Wednesday's loss to the Dodgers. Crawford attacked a Tony Gonsolin offering for a solo home run in the second inning, but the Giants would find little further offensive fun on the evening. Veteran shortstop Crawford has struggled to a .220/.319/.341 triple-slash with two homers and 10 RBI over 82 at-bats this season. Wednesday's home run was his first since mid-April.

Cardinals vs. Giants MLB BETTING PREDICTION

The Cardinals have won five of their last seven games against the Giants and 12 of their last 15 games when opening a new series. They’re also 20-6 in their last 26 games after scoring five runs or more in their previous game and are 29-11 in their last 40 road games dating back to last season. On the other side, the Giants are just 1-6 in their last seven games as an underdog.

MLB BETTING PREDICTION: ST. LOUIS CARDINALS -115