Padres vs. Giants Prediction

Padres vs. Giants, 4/11/22 MLB Betting Odds & Predictions

National League West rivals clash in San Francisco on Monday night when the Giants host the Padres at 9:45 p.m. ET. The Giants are currently moneyline favorites and the total is sitting at 8.5 – what’s the best bet when it comes to this divisional matchup?

Game Snapshot

957 San Diego Padres (+125) at 958 San Francisco Giants (-145); o/u 8.5

9:45 p.m. ET, Monday, April 11, 2022

Oracle Park, San Francisco, CA

San Diego Padres DFS SPIN

Jurickson Profar went 1-for-4 with a grand slam and a walk in the Padres' win over the Diamondbacks on Sunday. With the bases loaded in the top of the second, Profar took a 1-1 slider from Caleb Smith deep to left center field, giving the Padres a 4-0 lead. Profar has now hit two home runs over his first ten at-bats of 2022. For reference, he hit four home runs over 353 at-bats in 2021.

San Francisco Giants DFS Spin

Heliot Ramos went 2-for-3 with a run scored Sunday as the Giants took down the Marlins, 3-2. With two-out and nobody on in the bottom of the second, Ramos shot a 107.4 mph single up the middle that deflected off of Jazz Chisholm Jr., his first career big league hit. A top-five prospect in the Giants' farm system according to, Ramos is worth a speculative add in most fantasy formats. Though, how much playing time he receives will likely come down to how he's performing.


The over is 10-4-1 in the last 15 meetings between these two teams in San Francisco and is 12-3 in the last 15 meetings overall. The over is also 7-3 in the Padres’ last 10 games after scoring five runs or more in their previous game, is 5-1 in the Padres’ last six games on Monday and is 6-2 in the Giants’ last eight games played on Monday.



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