NHL Best Bets October 21 – Tuesday’s Top Picks & Analysis

NHL Best Bets October 21 – Tuesday’s Top Picks & Analysis NHL Best Bets October 21 – Tuesday’s Top Picks & Analysis

Last Updated on October 21, 2025 10:54 am by Michael Cash

NEW YORK — A busy Tuesday slate features heavyweight clashes in Boston and Toronto with a Canadian showdown in Ottawa. Our NHL Best Bets October 21 locks three plays with verified lines and links out to full previews for deeper reads: Panthers vs Bruins, Devils vs Maple Leafs, and Oilers vs Senators.

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NHL Best Bets October 21 — Today’s Picks

1) Panthers @ Bruins — Under 5.5 (−108) | 7:38 PM ET

  • Official Line: 5.5 (Over −112 / Under −108)
  • Angle: Florida’s forecheck and Boston’s slot denial trim rush chances and compress shot quality. The number gives headroom for a playoff-tempo script.
  • Full Preview: Panthers vs Bruins Prediction – East Power Tilt

2) Devils @ Maple Leafs — Over 6.0 (−105) | 7:08 PM ET

3) Oilers @ Senators — Oilers −1.5 (+145) | 7:08 PM ET

  • Official Line: Oilers −1.5 (+145) / Senators +1.5 (−170); Total 6.5 (Over −115 / Under −105)
  • Angle: Edmonton’s special-teams ceiling plus top-six cycle time tilt win-by-margin probability above the plus-price.
  • Full Preview: Oilers vs Senators – Expert Pick

Line Notes & Quick Hits – NHL Best Bets October 21

  • Panthers–Bruins: If the total toggles to 6.0 pre-puck, Under buyback strengthens given both creases manage second-chances well.
  • Devils–Leafs: Any drift to 6.5 invites small Under positions for middling; at a flat 6.0, pace leans Over.
  • Oilers–Sens: ML pressure favors Edmonton; puck-line plus price remains the preferred exposure over laying heavy moneyline juice.

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