Bills vs. 49ers NFL Week 5 Odds

bills 49ers nfl week 5 odds trends point spreads totals

SAN FRANCISCO, CA (The Spread) – One week after getting back on track in a 34-0 win over the Jets, the 49ers will once again take on a AFC East opponent when they host the Bills at 4:25PM ET on Sunday.

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BUFFALO: The Bills thought they may have had a win in hand last Sunday before the Patriots’ offense started to fire on all clyndiers. New England eventually pulled away with a 31-point fourth quarter and crushed Buffalo 52-28, dropping the Bills record to 2-2. Buffalo is now 2-2 against the spread, while the over has hit in three of the Bills’ first four games. C.J. Spiller has rushed for 341 yards while Scott Chandler has a team-high four touchdowns. Ryan Fitzpatrick, meanwhile, has thrown for 931 passing yards and Kyle Williams leads the team with 3.5 sacks.

SAN FRANCISCO: The 49ers ran their record to 3-1 on the year with a 34-0 shutout of the Jets in New York last Sunday. They’ve covered the spread in three of their first four games, with their only blemish being as a 6.5-point favorite in a 24-13 loss to the Vikings. Vernon Davis has four touchdowns to the lead the team, while Alex Smith has thrown for 784 yards. Frank Gore has a team-high 326 yards and Aldon Smith has 4.5 sacks.

ODDS: Oddsmakers from online sports book Bovada.lv have installed the 49ers as 9.5-point home favorites over the Bills, while the over/under total is currently sitting at 44.5 points. Buffalo is 2-2 overall and 1-1 on the road, while San Francisco is 3-1 overall and 1-0 at home.

TRENDS: The Bills are 4-1-1 against the spread in their last six games in October and 2-6-1 ATS in their last nine road games. The 49ers are 5-0 ATS in their last five games in October, 18-7-1 ATS in their last 26 games overall and 11-5-1 ATS in their last 17 games following an ATS win. The over is also 5-1 in the Bills’ last six games in Week 5 and 4-0 in the 49ers’ last four games in Week 5.

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