Twins vs Tigers Prediction September 8: Can Detroit Go Back to Back?

Twins vs Tigers Prediction September 8: Can Detroit Go Back to Back? Twins vs Tigers Prediction September 8: Can Detroit Go Back to Back?

The Minnesota Twins and Detroit Tigers meet in the middle game of their three-game set Tuesday night at Comerica Park, and the pitching matchup is a rerun. Drew Anderson and Dean Kremer squared off six days ago in Minneapolis. Detroit opened as a modest home favorite and the price has crept up since. Our headline play leans on the mismatch the market already sees, though the better price may sit elsewhere.

Last Updated: Tuesday, September 8, 2026

Minnesota Twins vs. Detroit Tigers — Time & How to Watch

WhereComerica Park, Detroit, Michigan
WhenTuesday, September 8 – 6:40 PM ET
TVDetroit SportsNet

Minnesota Twins vs. Detroit Tigers Betting Preview

Tuesday turns on the arms. Drew Anderson takes the ball for Detroit with a 3.73 ERA, a 1.30 WHIP and 101 strikeouts in 91 2/3 innings. He is not a conventional starter, though. Anderson has made just eight starts in 46 appearances, his longest outing of the year was the 5 2/3 innings he threw at Minnesota on September 2, and he walks 3.63 per nine. Minnesota counters with Dean Kremer, who is 2-5 with a 5.81 ERA.

Kremer’s history against Detroit is the loudest number on the board. He is 0-4 with a 9.12 ERA in five career outings against the Tigers, and six days ago he lasted four innings and surrendered four earned runs. He has now allowed at least four earned runs in three of his past four starts, so the trend is not confined to one opponent.

Neither club is chasing October. Detroit sits fourth in the AL Central at 66-78, with Minnesota third at 68-76. The Tigers limped home after being walked off three straight times in Cleveland, then steadied Monday with a 5-4 win behind homers from Riley Greene, Kevin McGonigle and Gleyber Torres. Minnesota stranded 10 runners and went 1-for-7 with runners in scoring position.

Minnesota Twins vs. Detroit Tigers Odds

Run LineMoneylineTotal
Twins+1.5 (-170)+119U 8.5 (-125)
Tigers-1.5 (+145)-142O 8.5 (+105)

Odds accurate as of Tuesday, September 8, 2026 via TheSpread.com. Odds change, get the latest MLB OddsFuturesProps

Minnesota Twins vs. Detroit Tigers — Who Is the Public Betting?

Twins35%65%Tigers

See the latest MLB Public Betting Splits and make smarter wagers!

Twins vs. Tigers Prediction — Can Kremer Solve a Lineup That Owns Him?

The starting pitching gap is the most load-bearing signal here, and it is not close. Anderson has the better ERA, the better WHIP and a strikeout rate near 10 per nine. Kremer’s problem is both general and specific: Detroit has beaten him repeatedly over his career, beat him again a week ago, and now sees him a second time inside seven days with fresh video. Quick second looks usually favor the hitters.

The market agrees, though not emphatically. Detroit opened at -136 and now sits at -142, a six-cent move in the Tigers’ direction. That is movement with the public rather than against it, so it confirms little on its own. Roughly two-thirds of run-line tickets sit on Detroit, and a price that has absorbed that much recreational money is no bargain. The -142 tag implies a break-even rate near 59 percent.

The case against Detroit is real. Anderson has not finished a sixth inning this season, so a bullpen that just lost three straight in walk-off fashion covers three or four innings again. Minnesota also hung 15 and 11 runs on this Tigers staff at Target Field in early September. That is the live counter-argument, and anyone taking the number should sit with it.

The Pick: Tigers Moneyline (-142)

Twins vs. Tigers Prediction — Will Two Short Starts Open the Floodgates?

Both starters project to hand the game over early, and that is the cleanest read on the total. Anderson’s season high is 5 2/3 innings and his walk rate invites traffic. Kremer has not finished six innings in any of his past four outings. Between them, the bullpens likely cover seven innings or more. Minnesota’s group is also a man short after Connor Prielipp threw four innings and 68 pitches in Monday’s opener.

The honest caveat is that this play leans on the same starter as the first one, so the two are correlated rather than independent. There is a case for the other side, too. Anderson misses bats at a high rate, Minnesota’s offense has been streaky, and what modest money has arrived went to the under, with the juice moving from -120 to -125. Still, the over is priced better than it opened, and that is where the value sits.

The Pick: Over 8.5 (+105)

Final Thoughts and Bonus Angle

The angle worth watching is the first-five-innings market. The edge here is specifically about the starters, and a first-five bet on Detroit would isolate Anderson against Kremer while removing a shaky Tigers bullpen from the equation. That market was not priced at publication, so it is a note, not a play. If a number posts before first pitch, it is the tidier expression of this read.

The Detroit run line at +145 will tempt anyone chasing the payout, but we are passing. Home favorites are structurally poor candidates at -1.5, because a ninth-inning lead ends the game before the margin can grow. With Anderson unlikely to see the seventh, two runs is a lot to ask. For more on this series, see Monday’s Twins vs. Tigers series-opener preview.

Watch the middle innings. If Kremer is at 70 pitches through four, Minnesota’s thinned bullpen inherits a long night and both positions improve at once. If he settles in and Anderson’s command wobbles, the game flips fast. To recap, the two plays are the Tigers Moneyline (-142) and the Over 8.5 (+105).

MLB Twins vs. Tigers FAQ: Tuesday September 8, 2026

What time does the Twins vs. Tigers game start?

First pitch is set for 6:40 PM ET on Tuesday, September 8, 2026, at Comerica Park in Detroit. This is the middle game of a three-game series between the Minnesota Twins and Detroit Tigers, and it follows Monday’s holiday matinee, which started at 3:10 PM ET.

What channel is the Twins vs. Tigers game on?

The game airs locally on Detroit SportsNet, the regional network that took over Tigers broadcast rights ahead of the 2026 season and carries roughly 140 games a year. It is also available through the Tigers and Twins in-market streams on MLB.TV for subscribers in each club’s territory.

Who is pitching for the Twins tonight?

Right-hander Dean Kremer starts for Minnesota. He is 2-5 with a 5.81 ERA and a 1.31 WHIP this season, and he faces Detroit right-hander Drew Anderson, who carries a 3.73 ERA. The two started against each other on September 2 in Minneapolis, six days before this rematch.

Who won the last meeting between the Twins and Tigers?

Detroit won the most recent meeting 5-4 on Monday, September 7, at Comerica Park. Kevin McGonigle, Riley Greene and Gleyber Torres homered for the Tigers, and Kenley Jansen closed it out. Trevor Larnach homered for Minnesota, which rallied for two runs in the sixth but fell short.

How many games are left in the Twins-Tigers series?

One game remains after Tuesday. The clubs close the three-game set on Wednesday, September 9, with a 1:10 PM ET first pitch at Comerica Park. Detroit is scheduled to start Keider Montero in the finale, with Minnesota expected to counter with Zebby Matthews.