Sunday’s full MLB slate features 16 matchups on May 24, 2026, with start times spanning from 12:15 PM ET to 7:20 PM ET.
I like a pair of teams playing in the afternoon on Sunday. Both teams are money line road underdogs.
Can 29-year-old Astros righty Peter Lambert pitch well enough to earn his third win of the season on Sunday? Will Rockies starter Jose Quintana improve his record to 3-2 in a road showdown with the Diamondbacks?
I'll make picks for both games below. Read on for our Sunday MLB Predictions May 24 article.
MLB Prediction Game 1
ASTROS VS CUBS DATE, TIME & HOW TO WATCH | |
|---|---|
| Where | WRIGLEY FIELD, CHICAGO, IL |
| When | SUNDAY, MAY 24, 2026, 2:20 PM ET |
| TV | MLB.TV |
ASTROS VS CUBS ODDS | |||
|---|---|---|---|
| Run Line | Moneyline | Total | |
| ASTROS | 1.5 (-153) | +143 | U 7.5 (-127) |
| CUBS | -1.5 (+133) | -174 | O 7.5 (+105) |
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ASTROS VS CUBS WHO IS THE PUBLIC BETTING? | |||
|---|---|---|---|
| ASTROS | 22% | 78% | CUBS |
See the latest MLB Public Betting Splits and make smarter wagers!
Houston Astros at Chicago Cubs May 24 MLB Prediction
The Houston Astros are in a good spot to secure an outright victory as money line road underdogs against the Chicago Cubs on Sunday afternoon.
Houston enters the matchup carrying strong momentum, boasting a 5-3 straight-up record over their last 8 games overall. Furthermore, the Astros consistently dominate this specific head-to-head rivalry, winning 4 of their last 5 meetings straight up against Chicago.
Starting pitcher Peter Lambert gives Houston a distinct advantage on the mound to stifle the Cubs' hitters. Lambert currently holds a career-best 3.57 ERA and a stellar 1.08 WHIP across his 6 starts this season.
His efficient pitching and the team's recent streak of success, combined with Chicago's current 7-game losing skid, provide immense value for backing the Astros to win on the road.
Pick: Houston Astros +143
MLB Prediction Game 2
ROCKIES VS DIAMONDBACKS DATE, TIME & HOW TO WATCH | |
|---|---|
| Where | CHASE FIELD, PHOENIX, AZ |
| When | SUNDAY, MAY 24, 2026, 4:10 PM ET |
| TV | MLB.TV |
ROCKIES VS DIAMONDBACKS ODDS | |||
|---|---|---|---|
| Run Line | Moneyline | Total | |
| ROCKIES | 1.5 (-125) | +159 | U 9.5 (-120) |
| DIAMONDBACKS | -1.5 (+105) | -194 | O 9.5 (+100) |
ROCKIES VS DIAMONDBACKS WHO IS THE PUBLIC BETTING? | |||
|---|---|---|---|
| ROCKIES | 10% | 90% | DIAMONDBACKS |
Colorado Rockies at Arizona Diamondbacks May 24 MLB Prediction
The Colorado Rockies are poised to secure an outright victory as money line road underdogs against the Arizona Diamondbacks on Sunday afternoon.
Colorado has an edge going into this divisional matchup, holding a 5-4 straight-up record over their last 9 games against Arizona. Furthermore, the Rockies perform exceptionally well behind starting pitcher Jose Quintana, winning 4 of his last 5 starts straight up.
Conversely, the Diamondbacks stumble frequently when starting pitcher Ryne Nelson takes the mound, dropping 5 of his last 7 starts straight up. Quintana's consistency and Arizona's pitching struggles both point toward Colorado winning outright on the road as money line underdogs on Sunday afternoon.
Pick: Colorado Rockies +159
Today's MLB Predictions
- Houston Astros +143
- Colorado Rockies +159