With Gavin Williams set to oppose Matthew Boyd in the pitching matchup, what’s the smart bet on Tuesday night’s Guardians vs. Cubs matchup? The first pitch is set for 8:05 p.m. ET.
Guardians vs. Cubs Game Info
Cleveland Guardians at Chicago Cubs
8:05 p.m. ET, Tuesday, July 1, 2025
Wrigley Field, Chicago, IL
Guardians vs. Cubs Public Betting & Odds
According to oddsmakers from online sportsbook Bovada.lv, the Cubs are -163 moneyline favorites over the Guardians, who are +146 underdogs. The total, meanwhile, sits at 8.5 runs.
As of this writing, our MLB Public Betting data page shows that the majority of public bettors are on Cleveland.
Starting Pitchers
Gavin Williams (CLE – RHP)
Season stats: 5–3, 3.68 ERA, 80.2 IP, 80 Ks
June performance: Delivered a stellar 2.57 ERA with 20 strikeouts over five starts
Outlook: With a rising profile and consistent recent performance, Williams will challenge the Cubs lineup with his heavy arsenal
Matthew Boyd (CHC – LHP)
Season stats: 7–3, 2.65 ERA, 91.2 IP, 82 Ks, stellar 1.10 WHIP
Form: Lights-out in his last six outings, posting a 1.49 ERA
Edge: As a team ERA anchor, Boyd continues to neutralize opponents and looks locked in after recovery from elbow injuries
Game Outlook & Keys to Watch
Boyd’s dominance vs. hard contact: With elite control and improved velocity, he’s tough to hit, especially for lefties.
Williams’ consistency: If he keeps his June form, he can navigate the Cubs’ lineup capably.
Cubs’ offense advantage: At home, backed by power hitters like Suzuki and Tucker, they force pressure early.
Guardians’ bullpen: Shoulders more responsibility if Williams exits early or gives up a few runs.
Guardians vs. Cubs Betting Prediction
Expect a quality start from Boyd, a couple of runs from Cleveland off Williams, but home-field bats push Chicago to a close win. Given Boyd’s red-hot form, Wrigley Field’s hitter-friendly park, and the Cubs’ batting strength, Chicago will overcome the 2-8 record it has versus Cleveland over the last 10 meetings between these two teams.
Guardians vs. Cubs MLB PREDICTION: CHICAGO CUBS -173