Friday MLB Predictions May 29: Can the Mets win as home favorites?

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Friday’s full MLB slate features 15 matchups on May 29, 2026, with start times spanning from 6:40 PM ET to 10:15 PM ET.

I like a pair of teams playing in the evening on Friday. Both teams are sending starting pitchers to the hill with ERAs of less than 2.80.

Can 25-year-old Twins righty Taj Bradley pitch well enough to earn his sixth win of the season on Friday? Will Marlins starter Max Meyer improve his record to 6-0 in a road matchup with the Mets?

I'll make picks for both games below. Read on for our Friday MLB Predictions May 29 article.

MLB Prediction Game 1

TWINS VS PIRATES DATE, TIME & HOW TO WATCH

WherePNC PARK, PITTSBURGH, PA
WhenFRIDAY, MAY 29, 2026, 6:45 PM ET
TVAPPLE TV

TWINS VS PIRATES ODDS

Run LineMoneylineTotal
TWINS1.5 (-180)+116O 8.0 (-110)
PIRATES-1.5 (+155)-139U 8.0 (-110)

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TWINS VS PIRATES WHO IS THE PUBLIC BETTING?

TWINS30%70%PIRATES

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Minnesota Twins at Pittsburgh Pirates May 29 MLB Prediction

The Minnesota Twins present compelling money line value as road underdogs against the Pittsburgh Pirates on Friday night.

Minnesota consistently demonstrates resilience in this spot, holding a profitable 22-21 straight up record as an underdog this season. The Twins carry strong momentum into PNC Park, going 6-4 straight up in their last 10 games overall.

Furthermore, Minnesota dominates this matchup, boasting a 4-1 straight up mark in their last 5 games against Pittsburgh.

Starting pitcher Taj Bradley provides a distinct advantage on the mound; the Twins are an impressive 6-3 straight up in his 9 starts this season. Expect Bradley to quiet the Pirates' bats and help his squad secure the road upset.

Pick: Minnesota Twins +116

MLB Prediction Game 2

MARLINS VS METS DATE, TIME & HOW TO WATCH

WhereCITI FIELD, QUEENS, NY
WhenFRIDAY, MAY 29, 2026, 7:10 PM ET
TVESPN UNLIMITED

MARLINS VS METS ODDS

Run LineMoneylineTotal
MARLINS1.5 (-210)+105O 7.5 (+105)
METS-1.5 (+175)-125U 7.5 (-125)

MARLINS VS METS WHO IS THE PUBLIC BETTING?

MARLINS43%57%METS

Miami Marlins at New York Mets May 29 MLB Prediction

The Miami Marlins are a good bet as money line road underdogs against the New York Mets on Friday night.

Miami has proven its capability against league opponents, carrying a 19-17 straight up record in National League games this season. The Marlins travel to New York with solid momentum, sporting a 4-2 straight up record in their last 6 games overall. Additionally, Miami historically dominates this divisional rivalry, securing an 8-2 straight up mark in their last 10 games against the Mets.

Starting pitcher Max Meyer gives the Marlins a significant edge on the mound; the team boasts an 8-3 straight up record in his 11 starts this season. Expect Meyer to keep rolling and toss another quality start in a Miami victory.

Pick: Miami Marlins +105

Today's MLB Predictions

  1. Minnesota Twins +116
  2. Miami Marlins +105
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