Diamondbacks vs. Padres Prediction

Arizona Diamondbacks vs. San Diego Padres, 5/21/2019 Predictions & Odds

The Padres took Game 1 of their series against National League West rivals the Diamondbacks last night. Will the Diamondbacks rebound with a small upset victory on Tuesday night when these foes meet again at 10:10 p.m. ET?

Game Snapshot & Odds

911 Arizona Diamondbacks (-109) at 912 San Diego Padres (-111); 7 runs

Monday, May 21, 2019

10:10 p.m. ET, Petco Park, San Diego, CA

Compare odds and from multiple different online sportsbooks and shop for the best lines at our new Baseball Odds & Betting Page.

Public Betting Trends

According to our MLB Public Betting Chart page, 77% of the betting tickets are on the Diamondbacks to beat the Padres on the moneyline.

Arizona Diamondbacks Fantasy Spin

Yasmany Tomas went 5-for-5 with four homers and eight RBI on Monday for Triple-A Reno on Monday. Tomas saw four pitches on Monday, and all four of them went over the fence. He now has 13 homers on the season, and he's slashing .311/.341/.598 in 42 games. Let's keep in mind that this four-homer game came in a contest that saw 33 runs -- 25 of them by Reno -- and the ball jumps out of PCL parks. It's also worth remembering that Tomas was a 30-homer player just two seasons ago. It probably won't come in Arizona, but he could be on an MLB roster if someone can figure out the (disastrous) financial aspects

San Diego Padres Fantasy Spin

Franmil Reyes hit a go-ahead two-run homer on Monday to help the Padres beat the Diamondbacks on Monday. With the Padres trailing 1-0 in the sixth, Reyes hit a two-run shot off of Luke Weaver to give San Diego a 2-1 lead and Reyes his 15th roundtripper of the season. He's also driven in 27 runs, and his slugging percentage improves to .596. The .258 average and .296 on-base percentage are nothing to write home about, but Reyes has tremendous power, and that makes him a solid -- if volatile -- fantasy option

MLB Betting Trends


The Diamondbacks are 3-7 in their last 10 games overall but 5-2 in their last seven road games versus a left-handed starter.

San Diego

The Padres are 10-25 in their last 35 games when playing the second game of a series.


The Diamondbacks are a perfect 4-0 in Zack Greinke’s last four starts versus the Padres and are 4-1 in his last five road outings versus San Diego. Arizona has also won 11 of Greinke’s last 16 road starts and is 17-7 in his last 25 outings coming off five days of rest. The Padres, meanwhile, are just 2-6 in their last eight games overall and are winless in their last four games following a win.

The Pick: Arizona Diamondbacks -109


MLB Headlines

MLB Predictions & Picks

Thumbnail Red Sox vs. Astros Game 6 Prediction The Astros will look to deliver the knockout blow to the Red Sox’ World Series hopes in Game 6 of the ALCS on Friday night at 8:08 p.m. ET. That said, with...
Thumbnail Dodgers vs. Braves MLB Prediction Game 4 of the NLCS will take place between the Braves and Dodgers at 8:08 p.m. ET on Wednesday night. Will the Dodgers even up the series at two games apiece or is...
Thumbnail Astros vs. Red Sox Game 5 Prediction The ALCS is now all tied at two games apiece following the Astros’ come-from-behind victory over the Red Sox on Tuesday night. Who has the edge in Game 5 this...
Thumbnail Astros vs. Red Sox Game 4 Prediction The Boston Red Sox have taken a 2-1 series lead in their best-of-seven matchup with the Houston Astros after routing the visitors on Monday night. Will tonight’s game...
Thumbnail Braves vs. Dodgers Game 3 Prediction The Braves are up 2-0 on the Dodgers in the NLCS but will they take a commanding 3-0 series lead when the two teams play Game 3 on...