Padres vs. Dodgers MLB Prediction

Padres vs. Dodgers, 4/22/21 MLB Betting Predictions & DFS Notes

The Dodgers and Padres will meet again on Thursday just four nights after playing a three-game series in San Diego. Listed as a large moneyline favorite, are the Dodgers the best play on the board?

Game Snapshot

907 San Diego Padres (+155) at 908 Los Angeles Dodgers (-175); o/u 7.5

10:10 p.m. ET, Thursday, April 22, 2021

Dodger Stadium, Los Angeles, CA

San Diego Padres DFS Spin

Trent Grisham had two singles, an RBI and a stolen base Wednesday against the Brewers. Grisham's one-out single in the third inning plated the game's first run, and he then immediately swiped his third base of the season. He also led off the fifth with a single but was retired on a force out. He got a late start to the season because of a hamstring injury, but Grisham has hit the ground running since then, boasting a .954 OPS with three homers and three steals through his first 11 contests.

Los Angeles Dodgers DFS Spin

Dodgers manager Dave Roberts said he expects Mookie Betts (forearm) to return Thursday against the Padres. Betts was held out of Tuesday's matinee game in Seattle after taking a pitch off his right forearm in the ninth inning Monday night. It's convenient that the defending World Series champions have a scheduled team off day on Wednesday ahead of Thursday's big series opener versus San Diego.

Padres vs. Dodgers Betting Prediction

The Padres are 16-41 in their last 57 games versus the Dodgers and are 19-48 in their last 67 meetings with the Dodgers in L.A. The Padres are also 1-4 in their last five games overall, are 2-5 in their last seven divisional games and are 1-7 in their last eight games versus an opponent with a winning record.



MLB Headlines

MLB Predictions & Picks

Thumbnail Braves vs. Astros Game 6 Prediction The Astros trailed 4-0 after the first inning of Game 5 and battled back to win 9-5 with their season on the line. Can they now even the series and force a Game 7...
Thumbnail Astros vs. Braves Game 3 Prediction With the World Series tied at one game apiece, the Astros and Braves will meet in Game 3 at 8:09 p.m. ET on Friday night. With Luis Garcia on the hill for Houston...
Thumbnail Braves vs. Astros Game 1 Prediction The World Series starts on Tuesday night with Game 1 between the Braves and Astros in Houston. Will the ‘Stros take the opening game as home chalk or is there a...
Thumbnail Dodgers vs. Braves Game 6 Prediction The Dodgers’ season will be on the line tonight at 7:08 p.m. ET when they play Game 6 of the NCLS versus the Braves. With so much uncertainty surrounding L.A.’s pitching...
Thumbnail Red Sox vs. Astros Game 6 Prediction The Astros will look to deliver the knockout blow to the Red Sox’ World Series hopes in Game 6 of the ALCS on Friday night at 8:08 p.m. ET. That said, with...