The Jacksonville Jaguars carry a nine-game regular-season winning streak into Denver on Sunday afternoon. The Broncos, meanwhile, are trying to wash out a 31-10 loss in Kansas City. Denver sits at -3 (+100) on the spread after opening at -2.5, and the total has ticked up to 45.5. That combination of a moved number and a lopsided public split is where this game gets interesting. Our two plays below lean on the direction of the line rather than the direction of the betting tickets.
Last Updated: Sunday, September 20, 2026
Jacksonville Jaguars vs. Denver Broncos — Time & How to Watch
| Where | Empower Field at Mile High, Denver CO |
| When | Sunday, September 20 – 4:05 PM ET |
| TV | CBS |
Jacksonville Jaguars vs. Denver Broncos Betting Preview
Jacksonville arrives at 1-0 after a 34-10 rout of Cleveland. Trevor Lawrence was close to flawless in that game. He completed 18 of 23 throws for 245 yards, four touchdowns and a 150.6 passer rating. The win extended a regular-season streak that now stands at nine games, dating to last November. Jacksonville’s pass rush did its part as well, with Josh Hines-Allen and Ventrell Miller both getting home.
Denver comes in at 0-1 and plays its first home game of the season. The Chiefs handled the Broncos 31-10 on Monday night. The tackling was the ugliest part of it. Denver missed more than two dozen tackles in that game, and Kenneth Walker III did most of the damage on the ground. Bo Nix threw an early touchdown to Evan Engram, then the offense went quiet.
Health favors the visitors. Jacksonville came out of the practice week with no game designations at all. Denver ruled out wide receiver Marvin Mims Jr. with a foot injury and listed running back RJ Harvey as questionable with a hamstring. The last meeting also belongs to Jacksonville. The Jaguars won 34-20 in Denver on December 21, 2025. For the full market picture on this game, see our Jaguars vs. Broncos odds breakdown.
Jacksonville Jaguars vs. Denver Broncos Odds
| Spread | Moneyline | Total | |
|---|---|---|---|
| Jaguars | +3 (-120) | +135 | O 45.5 (-110) |
| Broncos | -3 (+100) | -160 | U 45.5 (-110) |
Odds accurate as of September 20, 2026 via TheSpread.com. Odds change, get the latest NFL Odds – Futures – Props
Jacksonville Jaguars vs. Denver Broncos — Who Is the Public Betting?
| Jaguars | 69% | 31% | Broncos |
See the latest NFL Public Betting Splits and make smarter wagers!
Jaguars vs. Broncos Prediction — Why Is the Number Moving the Wrong Way?
Start with the disagreement. Sixty-nine percent of spread tickets are on Jacksonville. Yet the line opened at Denver -2.5 and now sits at Denver -3. The moneyline told the same story, moving from -135 to -160 on the home side. When a majority of the tickets land on one team and the price drifts the other way, the money behind those tickets is usually small. That is the cleanest signal on the board in this spot.
There is a football case underneath it. Denver is home for the first time, at altitude, and coming off a loss defined by a fixable problem. Missed tackles are a technique issue more than a talent issue, and they tend to regress. The Jaguars also have to travel two time zones on a short turn from a blowout win, which is the kind of spot where a team plays down to its opponent. Laying three points at even money is a better price than the same opinion costs on the moneyline.
The case against is real, though. Jacksonville has not lost a regular-season game since early November, and Lawrence is playing the best football of his career right now. He was close to perfect against Cleveland, and Jacksonville hung 34 points on this same Denver defense last December. If the Broncos cannot protect Nix any better than they did in Kansas City, this number will look silly by the fourth quarter. Still, at +100 with the market steaming toward Denver, the price justifies the risk.
The Pick: Broncos -3 (+100)
Jaguars vs. Broncos Prediction — Can Denver’s Offense Hold Up Its End?
The total opened at 44.5 and has climbed to 45.5, so the market expects more points than it did on Tuesday. The Denver offense argues otherwise. The Broncos scored 10 points in the opener and lost wide receiver Marvin Mims Jr. to a foot injury for this game. They now face a Jacksonville defense that generated multiple sacks and takeaways in Week 1. Lawrence’s group can score, but Jacksonville also held Cleveland to 10 points in the opener.
The counterargument is that Denver’s tackling problem does not fix itself in six days, and Jacksonville scored 34 points last week and 34 points in Denver last December. If Lawrence gets the same clean pocket he had against Cleveland, the over gets there by itself. The upside is that a shaky Denver offense caps the ceiling, and the number went up rather than down. That is the side worth taking.
The Pick: Under 45.5 (-110)
Final Thoughts and Bonus Angle
The obvious bonus angle here would be the Denver moneyline. We are passing on it. At -160, the moneyline asks for a 61.5% implied win rate from a team that just lost by three scores. The spread at +100 expresses the same view at a far better price, so there is no reason to pay up. Jacksonville’s +135 is the live-dog counterargument, and bettors who trust the streak over the line movement should take that route instead.
One more note for anyone building a card across the afternoon window: the same reverse-movement question shows up elsewhere on the slate, including in our Colts vs. Chiefs odds breakdown. Here are the two plays from this game.
Recap of picks: Broncos -3 (+100) and Under 45.5 (-110).
NFL Jaguars vs. Broncos FAQ: Sunday September 20, 2026
What time does the Jaguars vs. Broncos game start?
Kickoff is 4:05 p.m. ET on Sunday, September 20, 2026, which is 2:05 p.m. local time in Denver. It is part of the late Sunday afternoon window rather than a primetime national slot.
What channel is the Jaguars vs. Broncos game on?
The game airs on CBS, with Ian Eagle on play-by-play, Ross Tucker as analyst and Evan Washburn on the sideline. It streams locally on Paramount+, with out-of-market coverage available through NFL+ and NFL Sunday Ticket.
Where are the Jaguars and Broncos playing?
The teams meet at Empower Field at Mile High in Denver, Colorado. It is Denver’s first home game of the 2026 season. Jacksonville opened at home against Cleveland, so this is the Jaguars’ first road trip of the year.
Who is starting at quarterback for the Jaguars and Broncos?
Trevor Lawrence starts for Jacksonville and Bo Nix starts for Denver. Lawrence threw four touchdown passes in the opener against Cleveland. Nix threw one touchdown in the loss at Kansas City. Neither quarterback appeared on this week’s injury report with a designation.
Who won the last meeting between the Jaguars and Broncos?
Jacksonville won the last meeting 34-20 on December 21, 2025, also at Empower Field at Mile High. The Jaguars scored 34 points in that game and have not lost a regular-season contest since.