NBA Playoff Predictions May 13: Can Detroit take a 3-2 series lead?

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Wednesday has 1 game on the NBA slate as the second full week of May 2026 marches on. It's a Game 5 in the second round of the NBA Playoffs.

Can the Pistons cover the 3.5-point spread as home favorites against the Cavaliers? Will both teams combine to score more than the total of 212.5 points?

I'll make picks for the spread and total below. Read on for our NBA Playoff Predictions May 13 article.

CAVALIERS VS PISTONS DATE, TIME & HOW TO WATCH

WhereLITTLE CAESARS ARENA, DETROIT, MI
WhenWEDNESDAY, MAY 13, 8 PM ET
TVESPN

CAVALIERS VS PISTONS ODDS

SpreadMoneylineTotal
CAVALIERS4 (-115)+145U 212.5 (-110)
PISTONS-4 (-105)-170O 212.5 (-110)

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CAVALIERS VS PISTONS WHO IS THE PUBLIC BETTING?

CAVALIERS31%69%PISTONS

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Cavaliers vs. Pistons Game 5 Spread Prediction

The Detroit Pistons are poised to cover the 4-point spread as home favorites against the Cleveland Cavaliers in Game 5 of their second-round series on Wednesday night.

Despite this series being even at 2-2, Detroit’s situational trends are hard to ignore. The Pistons excel at bouncing back, boasting a 14-12 ATS record after a loss this year.

They also protect their home court, going 25-21 ATS as the home team this season. Furthermore, Detroit handles familiar foes well, sitting at 35-28 ATS in conference games in 2025-26.

With momentum building from a 4-2 ATS mark in their last 6 games overall, the Pistons' balanced attack and home-court energy should help them secure the Game 5 win and cover.

Pick: Detroit Pistons -4

Cavaliers vs. Pistons Game 5 Total Prediction

Expect a high-scoring affair as the Cleveland Cavaliers and Detroit Pistons appear primed to combine for more than the total of 212.5 points on Wednesday night.

Situational trends point heavily toward the over. The over is 11-9 in Detroit's division games this season. The Pistons also bounce back offensively, seeing the over go 14-11-1 following a loss this year. Additionally, the over is 26-22 in Detroit's games when they are facing an opponent on equal rest.

Meanwhile, Cleveland's offense has surged in the postseason, as the over is 7-4 in their playoff games in 2026. With both teams rested and highly motivated, look for an offensive shootout that easily eclipses the 212.5-point total in Wednesday's Game 5.

Pick: Cleveland Cavaliers vs. Detroit Pistons Over 212.5

Today's NBA Playoff Predictions

  1. Detroit Pistons -4
  2. Cleveland Cavaliers vs. Detroit Pistons Over 212.5
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