Will the Broncos keep rolling and hold onto the No. 1 seed in the AFC with a victory over the Jaguars? Or will Jacksonville secure a small upset in Sunday’s Jaguars vs. Broncos clash at 3:05 p.m. ET?
Jaguars vs. Broncos Game Day Information
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Matchup: Jacksonville Jaguars (10–4) at Denver Broncos (12–2)
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Date & Time: Sunday, December 21, 2025 — 4:05 PM ET / 2:05 PM MT
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Location: Empower Field at Mile High — Denver, Colorado
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TV: FOX
Opening line: Jaguars +3 / Broncos -3
Key Stats & Storylines
Jaguars (10–4)
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Jacksonville has surged with a 5-game win streak heading into Denver.
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Trevor Lawrence leads a dynamic offense with over 3,200 passing yards and 23 TDs this season.
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Travis Etienne Jr. is a versatile offensive weapon with nearly 950 rushing yards and a team-high in touchdowns.
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Wideout Jakobi Meyers has provided a major boost since joining midseason.
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Rookie RB Bhayshul Tuten is out due to surgery, which could limit depth behind Etienne.
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Defensive playmakers like LB Devin Lloyd anchor a unit that creates turnovers.
Broncos (12–2)
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Denver tops the AFC with an 11-game win streak and is undefeated at home.
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QB Bo Nix has been efficient, throwing more than 3,200 yards and mixing well with his weapons.
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Nik Bonitto and Denver’s pass rush rank among the league’s best, creating pressure and chaos for opposing QBs.
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Broncos have dealt with RB J.K. Dobbins’s absence and leaned on depth like RJ Harvey in the backfield.
Team Stats Snapshot
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Jaguars average ~26–27 PPG; Broncos ~24–26 PPG.
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Denver’s defense ranks elite in limiting rush yards and points allowed.
Public Betting Tickets
Numbers update frequently — check the latest on the NFL public betting chart and learn usage basics in our public betting guide.
Jaguars vs. Broncos Picks & Predictions
This AFC clash projects as a high-stakes showdown with playoff implications for both teams. Jacksonville’s explosive offense and streaky play make them dangerous, but Denver’s stifling defense and home-field advantage give them the edge. I’m backing the Broncos to control the game in key moments and secure a home victory in a competitive contest.
Final Score Prediction: Broncos 27, Jaguars 21 (Take Denver -3)