Last Updated on October 7, 2025 9:58 am by Michael Cash
NFL Week 6 opening odds sharpened fast. Here are the verified current spreads, totals and moneylines for every game, plus quick market notes.
NFL Week 6 opening odds hit the board and stabilized into a clear consensus by Tuesday morning. Below are the current verified numbers (spread/total/moneyline) for each matchup. Keep our NFL odds board and the public betting chart open for intraday moves.
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NFL Week 6 — Verified Current Odds
TNF — Eagles @ Giants (Thu 8:15 ET)
- Spread: Eagles −7
- Total: 41.5
- Moneyline: Eagles −395 / Giants +310
London — Broncos vs Jets (Sun 9:30 ET)
- Spread: Broncos −7.5
- Total: 43.5
- Moneyline: Broncos −375 / Jets +310
Early Window (Sun 1:00 ET)
- Browns @ Steelers: Steelers −4.5 • Total 37.5 • ML PIT −238 / CLE +195
- Cardinals @ Colts: Colts −6.5 • Total 47.5 • ML IND −298 / ARI +240
- Chargers @ Dolphins: Chargers −4.5 • Total 44.5 • ML LAC −230 / MIA +190
- Rams @ Ravens: Rams −7.5 • Total 44.5 • ML LAR −410 / BAL +320
- Seahawks @ Jaguars: Jaguars −1.5 • Total 46.5 • ML JAX −110 / SEA −110
- Cowboys @ Panthers: Cowboys −3.5 • Total 49.5 • ML DAL −180 / CAR +154
- Patriots @ Saints: Patriots −3.5 • Total 45.5 • ML NE −185 / NO +154
Late Window (Sun 4:05 / 4:25 ET)
- Titans @ Raiders: Raiders −4.5 • Total 41.5 • ML LV −230 / TEN +190
- Bengals @ Packers: Packers −14.5 • Total 44.5 • ML GB −1450 / CIN +800
- 49ers @ Buccaneers: Buccaneers −3 • Total 47.5 • ML TB −166 / SF +136
SNF — Lions @ Chiefs (Sun 8:20 ET)
- Spread: Chiefs −1.5
- Total: 50.5
- Moneyline: Chiefs −120 / Lions even
MNF Doubleheader (Mon)
- Bills @ Falcons (7:15 ET): Bills −4.5 • Total 48.5 • ML BUF −205 / ATL +170
- Bears @ Commanders (8:15 ET): Commanders −4.5 • Total 50.5 • ML WAS −230 / CHI +190
Quick Market Notes
- Biggest favorites: Packers −14.5 vs Bengals; Rams −7.5 at Ravens.
- Tightest line: Seahawks @ Jaguars (JAX −1.5; near pick’em ML).
- Highest total zones: Lions–Chiefs 50.5; Commanders–Bears 50.5.
- Lower total clusters: Browns–Steelers 37.5; several mid-40s drifting on weather/news.
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