Last Updated on September 28, 2025 8:39 am by Michael Cash
Looking for the latest NFL Week 4 Sunday odds and quick betting angles? Start with live NFL public betting percentages, browse the NFL odds & picks hub, and check our weekly SuperContest expert card. Below, you’ll find the current spread and total for every Sunday matchup plus quick notes to help you time your bets.
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NFL Week 4 Sunday Odds — London Kickoff
Neutral-site openers often move early; meanwhile, totals can be sticky until inactives.
- Vikings vs. Steelers (neutral) — Spread: MIN -2.5 • Total: 41.5
NFL Week 4 Sunday Odds — Early Window (1:00 PM)
Early kickoffs tend to firm up 60–90 minutes pre-game; therefore, watch for buy/sell points around 3 and 7.
- Commanders at Falcons — Spread: ATL -1.5 • Total: 44.5
- Saints at Bills — Spread: BUF -16.5 • Total: 48.5
- Panthers at Patriots — Spread: NE -5.5 • Total: 43.5
- Lions at Browns — Spread: DET -9.5 • Total: 44.5
- Titans at Texans — Spread: HOU -7 • Total: 38.5
- Giants at Chargers — Spread: LAC -6 • Total: 43.5
NFL Week 4 Sunday Odds — Late Window (4:05/4:25 PM)
By late afternoon, limits are higher; consequently, sharper moves can appear closer to kick.
- 49ers at Jaguars — Spread: SF -3 • Total: 47.5
- Rams at Colts — Spread: LAR -3.5 • Total: 49.5
- Chiefs at Ravens — Spread: BAL -2.5 • Total: 48.5
- Raiders at Bears — Spread: CHI -1.5 • Total: 47.5
NFL Week 4 Sunday Odds — Sunday Night Football
Prime-time numbers often gravitate to key prices; however, prop markets may move more aggressively.
- Packers at Cowboys — Spread: DAL -7 • Total: 47.5
Market Notes & How to Use These Sunday Odds
First, anchor to key numbers (3 and 7) and plan entries around them. Next, reconcile tickets % with price action; if the crowd is heavy on a favorite while the line stalls, consider patience. Finally, re-check outdoor weather and inactive lists—late scratches can nudge totals by a half-point or more.
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