Last Updated on September 13, 2025 8:10 am by Anthony Rome
In this Arkansas vs Ole Miss prediction, two SEC teams meet in a high-profile Saturday night game in Oxford. Ole Miss brings explosive offense and home-field heat, while Arkansas is the hungry underdog that can hang around if they protect the ball and control field position. Below you’ll find event details, the market links, matchup notes, and one crisp pick.
Event Information
- Matchup: Arkansas Razorbacks at Ole Miss Rebels
- Date: Saturday, September 13, 2025
- Kickoff: 7:00 p.m. ET / 6:00 p.m. CT
- Stadium: Vaught-Hemingway Stadium — Oxford, MS
- TV: ESPN
Betting Odds & Market Info
- Spread: Arkansas +6.5 / Ole Miss -6.5
- Total (O/U): 62.5
Get the live lines at Bovada and monitor public ticket/money splits at the College Football Public Betting Chart.
What matters to bettors
- Ole Miss offense: High-octane, chunk-play driven — when their passing game clicks they can pile up points in a hurry. Their home environment amplifies that.
- Arkansas counter: The Razorbacks need turnover creation, third-down stops, and special-teams angles. Their best path is limiting explosive plays and flipping the field with turnovers or returns.
- Game-script pivots: Late rotation, red-zone efficiency, and pressure on the QB will swing this line. A couple of early big plays can make this a shootout; a clean, possession-style script keeps the number within reach for Arkansas.
Prediction & Best Bet
Predicted Score: Ole Miss 38, Arkansas 28
Best Bet: Arkansas +6.5 (small–medium unit)
Why I like it: Ole Miss is the more dangerous offense, but a 6.5-point number buys meaningful insurance in a rivalry game that can produce special-teams swings and late substitutions. Arkansas has shown the ability to cover when they protect the ball and force a few turnovers; against a Rebels offense that can be boom-or-bust, the Razorbacks plus the points is a pragmatic value ticket. If you want the cleaner win, lean Ole Miss straight up. But for upside and protection, take Arkansas +6.5.