Last Updated on July 8, 2025 9:05 am by Anthony Rome
The Philadelphia Phillies aim to bounce back in Game 2 of this three-game set after dropping Monday’s opener 3–1. With Cristopher Sánchez to take the mound, Philly looks to flip the script against a confident Giants squad coming off a solid win. But is Philadelphia the smart play in tonight’s Phillies vs. Giants matchup?
Game Matchup & Betting Odds
Philadelphia Phillies at San Francisco Giants
9:45 p.m. ET, Tuesday, July 8, 2025
Oracle Park, San Francisco, CA
Phillies vs. Giants Betting Odds
According to oddsmakers from online sportsbook Bovada.lv, the Phillies are -132 moneyline favorites to beat the Giants, who are +122 moneyline underdogs. The total, meanwhile, is sitting at 7.5 runs.
Phillies vs. Giants Public Betting: Bettors Backing Underdog
As of this writing, our MLB Public Betting Page shows that 59% of the bets are on the Giants moneyline. That said, this page is updated frequently so make sure that you click on the link provided so that you’re getting the most updated information.
Pitching Matchup
PHI: Cristopher Sánchez (7–2, 2.68 ERA)
Sánchez has been a force this season, making this outing his third career start against the Giants. He’s impressed in previous meetings, totaling 19 strikeouts in 13 innings and allowing just two earned runs—highlighting his dominance and comfort against San Francisco’s lineup.
SF: Landen Roupp (6–5, 3.48 ERA)
Roupp’s dependable work stabilized the Giants’ rotation early on. He’ll need to hold off Philadelphia’s potent offense and keep his pitch count manageable to stay effective deep into the game.
Key Storylines
The Phillies leaned on Sánchez’s strikeout capabilities Monday, and analysts are backing his Over 5.5 strikeouts again—San Francisco bags the 5th-highest strikeout rate versus lefties this season. Conversely, the Giants’ bullpen has been rock-solid, with Monday’s victory secured via Tyler Rogers and closer Camilo Doval.
Offensively, Philly has cooled of late—managing just one run Monday—so timely hits from Krail Schwarber or Bryce Harper will be crucial. On the flip side, San Francisco bats are riding a wave of momentum, and with their bullpen locked in, they’re primed for another tight game.
Phillies vs. Giants MLB BETTING PREDICTION
Expect a classic pitcher’s duel. Sánchez looks to overpower a Giants lineup he’s previously mastered, while Roupp must avoid big innings. Strategic bullpen deployment will likely determine the outcome—Philly will test San Francisco’s depth late, but the Giants’ late-inning arms (.…Doval with 14 saves, Rogers strong) provide a formidable defense.
Phillies vs. Giants MLB Playoffs Prediction: UNDER 7.5