Last Updated on September 8, 2022 11:37 am by Anthony Rome
Bills vs. Rams Over/Under Prediction
The 2022 NFL Season kicks off on Thursday night when the defending Super Bowl champion Rams host the Bills at 8:20 p.m. ET. The total for tonight’s game sits at 51.5.
Is that number too high for a season-opening matchup?
Game Matchup & Betting Odds
451 Buffalo Bills (-2.5) at 452 Los Angeles Rams (+2.5); o/u 51.5
8:20 p.m. ET, Thursday, September 8, 2022
SoFi Stadium, Los Angeles, CA
Bills vs. Rams Public Betting Information
Our NFL Public Betting Information page indicates that 62% of public bettors are currently backing the 49ers when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
Buffalo Bills DFS Spin
Bills WR Isaiah McKenzie (groin) was listed as a full participant in Tuesday’s practice. Sean McDermott said earlier today that he expected McKenzie to play. With back-to-back full practices, it seems overwhelmingly likely that McKenzie will be able to take his normal snap load in Thursday’s opener against the Rams. He’ll be a hard-to-trust WR4 until we get more of a read on where Ken Dorsey’s distributing offensive targets to, but McKenzie could return value.
Los Angeles Rams DFS Spin
Van Jefferson (knee) is out for Week 1 against the Bills. Jefferson missed most of the summer recovering from a cleanup procedure on his knee and isn’t quite ready to play. Ben Skowronek is expected to be next man up for the Rams as the third wideout, though we may also see some Tutu Atwell.
Bills vs. Rams Betting Trends
Favorite is 4-1 ATS in their last 5 meetings
Bills are 4-1 ATS in their last 5 meetings
Over is 4-1 in the last 5 meetings
Bills vs. Rams Over/Under Prediction:
With Josh Allen, Stefon Diggs, Matthew Stafford and Cooper Kupp highlighting tonight’s matchup, there’s plenty of firepower tonight for the over to cash. That said, these are also two of the better defenses in the league and this is a high total for a Week 1 matchup. One bad quarter offensively by both teams could get over bettors off-track and allow for the under to cash easily. The under is 7-2 in the Bills’ last nine Week 1 matchups, is 20-8-1 in the Rams’ last 39 games when favored and has hit in 19 of L.A.’s last 26 games as a home favorite.
NFL WEEK 1 OVER/UNDER PREDICTION: BILLS/RAMS UNDER 51.5