INDIANAPOLIS (AP) -Colts safety Bob Sanders, last season's NFL Defensive Player of the Year, was inactive for Sunday's game against Houston.
Sanders missed Wednesday's practice, taking a regular rest day, then participated in Thursday's workouts. But after hurting his knee, Sanders sat out again Friday. The Colts have neither disclosed which knee Sanders injured nor how extensive the injury may be.
Earlier this season, Sanders missed five games with knee and ankle injuries before returning for the Colts' last two games, victories over New England and Pittsburgh.
Houston listed three starters as inactive. Defensive tackle Amobi Okoye (high ankle sprain), linebacker Morlon Greenwood (leg) and quarterback Matt Schaub (left knee) were all out after being listed as doubtful this week.
Quarterback Sage Rosenfels replaced Schaub. Rosenfels committed three turnovers in the final five minutes of this season's first contest against Indianapolis, allowing the Colts to rally from a 17-point deficit for a 31-27 victory at Houston.

Recent NFL Discussions

Top NFL Public Bets

NFL Top Stories

Thumbnail How to bet Current Super Bowl Odds Many sports bettors might not know how online bookie agents are turning a profit via futures betting.
Thumbnail Packers vs. Steelers Total Pick Will Sunday night's matchup between the Green Bay Packers and Pittsburgh Steelers fall under the betting total? Kickoff is set for 8:30 p.m. ET.
Thumbnail Saints vs. Rams Total Pick Will the over cash for bettors on Sunday when the Los Angeles Rams host the New Orleans Saints in a pivotal conference matchup at 4:25 p.m. ET?
Thumbnail Broncos vs. Raiders Total Pick Is the under a great play on Sunday afternoon when the Oakland Raiders will host the struggling Denver Broncos? This AFC West rivalry will kick off at 4:25 p.m....
Thumbnail Seahawks vs. 49ers Total Pick Will the Seattle Seahawks and San Francisco 49ers put up enough points on Sunday when the NFC West rivals clash at Levi's Stadium on 4:05 p.m. ET?

NFL Team Pages