Rams vs. 49ers SNF Prediction

Rams vs. 49ers, 10/18/20 NFL Week 6 Betting Predictions

The Sunday Night Football matchup in Week 6 features NFC West rivals the Rams and 49ers at 8:20 p.m. ET as San Francisco looks to get back to .500 with a win and L.A. attempts to improve to 5-1 on the season. What’s the best play for bettors looking to enjoy this one in Santa Clara tonight?

Game Snapshot

273 Los Angeles Rams (-3) at 274 San Francisco 49ers (+3); o/u 51.5

8:20 p.m. ET, Sunday, October 18, 2020

Venue: Levi’s Stadium, Santa Clara, CA

TV: NBC

Los Angeles Rams DFS Spin

Jared Goff completed 21-of-30 passes for 309 yards, two touchdowns, and an interception in the Rams' 30-10 Week 5 win over Washington. Goff shredded the Washington secondary on play action throughout the first half. As usual, pass catchers were wide open against the Football Team's leaky coverage unit. Goff was efficient in the Rams' low-volume passing attack a week after struggling against the Giants. He won't be a starting option in 12-team leagues next week against the 49ers.

San Francisco 49ers DFS Spin

Jimmy Garoppolo (ankle) will start in Week 6 against the Rams. Garoppolo practiced every day this week "without limitations" and, per coach Kyle Shanahan, looked healthier. Sunday is a tantalizing spot opposite Los Angeles' defense but Garoppolo should not be trusted for re-draft leagues until he has proved he's fully removed from his high-ankle sprain. He ranks as RotoPat's QB17 for Week 6.

Rams vs. 49ers Betting Prediction

The 49ers have covered the spread five of the last six times they’ve been listed as an underdog and are 6-2 against the number in their last eight games when facing an opponent with a winning record. San Francisco has covered in six of its last eight home games when facing a team with a winning record on the road, too. The Rams, meanwhile, are just 8-22-1 against the spread in their last 31 games after allowing less than 150 yards passing in their previous game. They’re also 1-4 against the number in their last five games when playing in Week 6.

NFL WEEK 6 BETTING PREDICTION: SAN FRANCISCO 49ERS +3

NFL Predictions & Picks

Thumbnail Cowboys vs. 49ers Over/Under Prediction Despite the explosiveness on both sides, is the under the best play for Sunday evening’s NFL playoffs matchup between the Cowboys and 49ers at 6:30 p.m. ET?
Thumbnail Cowboys vs. 49ers Prediction The Cowboys and 49ers will put a bow on the Divisional round of the NFL playoffs at 6:30 p.m. ET. Will Dallas hang with San Francisco as a 3.5-point underdog or are the Niners...
Thumbnail Bengals vs. Bills Over/Under Prediciton The total for Sunday’s NFL Divisional round matchup between the Bengals and Bills opened at 50 but has been bet down to 48.5. Is the under the safe play when...
Thumbnail Bengals vs. Bills Prediction The Bengals and Bills will square off in the Divisional round of the NFL playoffs on Sunday at 3:00 p.m. ET. Is 5.5 too much to la with the host Bills or will Buffalo...
Thumbnail Jaguars vs. Chiefs Prediction & Odds The Divisional round of the NFL playoffs begins on Saturday with a matchup at Arrowhead Stadium between the Chiefs and Jaguars at 4:30 p.m. ET. Is 9 too much to...

NFL Headlines