NEW YORK (AP) -Ben Sheets ruined Johan Santana's Shea Stadium debut, outpitching the Mets' new ace in the Milwaukee Brewers' 5-3 win over New York on Saturday.
Home runs by Bill Hall, Rickie Weeks and Gabe Kapler helped Milwaukee come from behind and Sheets (2-0) overcame a shaky start to help Brewers end a three-game losing streak.
Santana struggled and the Mets' three-game winning streak was snapped. He lasted 6 2-3 innings and allowed five runs and six hits with two walks, striking out seven and throwing two wild pitches.
Santana (1-2), who allowed 33 home runs with Minnesota last season to lead the league, worked his way out of a number of jams but was hurt by the long ball.
Sheets allowed three runs and five hits in 7 2-3 innings with five strikeouts and two walks. After giving up two runs in the first inning and leaving the bases loaded in the second, he was untouchable, retiring 18 consecutive batters into the eighth inning.
Diamondbacks 10, Rockies 3
PHOENIX (AP) - Justin Upton went 3-for-3 with four RBIs, including a three-run home run, to power Arizona to its eighth consecutive victory.
The 20-year-old outfielder, the first overall pick in the 2005 draft, boosted his average to .415, including five home runs with 10 RBIs.
Dan Haren limited the Rockies to a run and five hits in six innings and Arizona improved to 5-0 against Colorado this season. Haren (2-0) struck out seven and walked two.
The Diamondbacks have outscored Colorado 38-10 in the five games. Last October, the Rockies swept Arizona in the NLCS.
Franklin Morales (0-1), who blanked Arizona on two hits over six innings in a no-decision last week in Colorado, allowed seven runs and seven hits in four-plus innings on Saturday. He struck out one, hit a batter and walked three.
Cardinals 8, Giants 7, 10 innings
SAN FRANCISCO (AP) - Chris Duncan lined a go-ahead single to left with the bases loaded in the 10th and St. Louis battered the San Francisco bullpen to spoil a gem by Giants starter Matt Cain.
Cain had a no-hitter heading into the seventh, but Albert Pujols ended it with a leadoff double. It was the fourth time in Cain's career he hadn't allowed a hit going into the seventh.
St. Louis took advantage of two walks, one intentional, and a hit batsman by Erick Threets (0-1) in the 10th. Jason Isringhausen (1-0) blew his first save in six chances this season in the ninth but still earned the win, then Anthony Reyes finished for his first save in as many tries.
The Cardinals had gone ahead in the top of the ninth on Ryan Ludwick's two-run homer off Brad Hennessey. Duncan pulled the Cardinals within 5-3 on a solo home run off Tyler Walker leading off the eighth, then Rick Ankiel hit a tying two-run shot two batters later. Walker, who had not given up a run in his first five outings, was booed walking off the field.
Cain also homered to break a scoreless tie and John Bowker hit a three-run shot in his major league debut for San Francisco, which blew a 5-0 lead to deny Cain his first victory.
Braves 10, Nationals 2
WASHINGTON (AP) - Jeff Francoeur had two home runs and a career-high seven RBIs, and Atlanta handed Washington its ninth straight loss.
Francoeur hit a three-run home run in the first inning, a two-run single in the fourth and a two-run shot in the sixth. He came in with four RBIs in 10 games this season.
The Nationals' skid is their longest since moving to Washington in 2005 from Montreal. The last time the franchise lost nine in a row was the final nine games of the 2000 season.
John Smoltz (2-0) pitched six innings and allowed one run and five hits. He walked two and struck out five - leaving him just 14 strikeouts shy of 3,000.
After a 91-minute rain delay in the first day game at Nationals Park, Francoeur hit a three-run homer to left in the first off John Lannan (0-2) to make it 4-0.
Phillies 7, Cubs 1
PHILADELPHIA (AP) - Cole Hamels allowed one hit over seven innings, and Pedro Feliz and Ryan Howard hit two-run homers for the Phillies.
Derrek Lee's double with one out in the fourth was the only hit off Hamels (2-1), who struck out five, walked two and got 13 outs on flyballs.
The Phillies won their second straight game without shortstop Jimmy Rollins. The 2007 NL MVP has been out of the starting lineup four consecutive games.
Ted Lilly (0-2) allowed five runs and seven hits in 4 1-3 innings. The left-hander hasn't pitched five innings in his first three starts and has a 9.95 ERA.
Pirates 4, Reds 3
PITTSBURGH (AP) - Nate McLouth, the surprise major league hits leader, singled in the go-ahead run and had two more hits, and the Pirates won consecutive games for the first time this season.
Ronny Paulino had a two-run single in the second inning against Bronson Arroyo (0-2), who remained winless in four career starts against his former club.
Ian Snell (2-0), the only Pirates starting pitcher to win in their 11 games this season, pitched 6 1-3 innings for the victory despite allowing nine hits and walking two.
Astros 5, Marlins 0
HOUSTON (AP) - Brandon Backe (1-1) gave up five hits and five walks with two strikeouts in five innings, and Lance Berkman hit a two-run homer and scored another run for, the Astros.
The Marlins had a four-game winning streak snapped and lost for the first time in five road games.
Florida starter Andrew Miller (0-2) gave up eight hits and four walks with six strikeouts in five innings. He allowed only one hit after the Astros scored all five of their runs in the first two innings.
Dodgers 11, Padres 1
LOS ANGELES (AP) - Andre Ethier went 3-for-5 with a two-run homer, Rafael Furcal and Matt Kemp each hit their first homers of the season and the Dodgers snapped a four-game skid.
Derek Lowe (1-0) allowed a run and four hits over eight innings, striking out six and walking none before giving way to the bullpen. The right-hander retired 20 of his last 21 batters and also drove in a career-high three runsto improve his record against the Padres at Dodger Stadium to 4-0. He is 0-3 in seven starts at Petco Park.
Chris Young (1-1) threw 80 pitches in three-plus innings, allowing seven runs, seven hits and four walks. The right-hander, who had the lowest opponents' batting average in the majors each of the previous two seasons, retired only nine of the 21 batters he faced. One of the runs against him was unearned, the result of his own fielding error.

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