SAN FRANCISCO (AP) - Running back Brandon Jacob's debut with the San Francisco 49ers will have to wait at least another week.
Jacobs is among those inactive for San Francisco against the Buffalo Bills on Sunday. The big, burly former New York Giants running back has not played since injuring his left knee in the preseason. He practiced this week without limitations and had declared himself healthy enough to play.
Rookies LaMichael James and A.J. Jenkins also were inactive for the 49ers.
The Bills got a boost with safety Jairus Byrd (hip) and wide receiver Ruvell Martin (ankle) on the active roster. Both were listed as questionable earlier in the week. Martin also plays on special teams.

Recent NFL Discussions

uconn / smu college hoops on Sat, Feb 2017 by armyranger
Carolina Wise Guy.....What? on Thu, Feb 2017 by Timmy1961
2017 NFL Draft Props on Fri, Feb 2017 by Blade
Handicapping Week 1 on Fri, Feb 2017 by Blade
Blade what time do you get up on Thu, Feb 2017 by Blade
Advertisement

Top NFL Public Bets

NFL Top Stories

Thumbnail Broncos could show interest in Romo Will the Broncos at least discuss adding Tony Romo if he were released by the Cowboys?
Thumbnail Vikings noncommittal to AP Vikings general manager Rick Spielman was noncommittal when speaking about Adrian Peterson on Thursday.
Thumbnail Krik Cousins Next Team Prop Odds Which team will Kirk Cousins be playing for in Week 1 of the 2017 NFL regular season?
Thumbnail Tony Romo Next Team Prop Odds Which team will Tony Romo play for when the 2017 NFL regular season begins? Oddsmakers have weighed in.
Thumbnail Taylor could be fit in Cleveland Could current Bills Tyrod Taylor be a fit for the quarterback-needy Browns next season?

NFL Team Pages