Clemson (3-2, 1-1 ACC) at Wake Forest (3-1, 1-0), 7:30 p.m. (ESPN).
Line: Wake Forest by 2 1/2.
Series record: Clemson leads 56-16-1.
Last meeting: 2007, Clemson 44-10.
What's at Stake
The inside track in the ACC Atlantic Division race. Clemson and Wake Forest were the consensus favorites in the preseason, and the Tigers can't afford a second consecutive loss in league play.
Key Matchup
Wake Forest's run defense against Clemson RBs James Davis and C.J. Spiller. The Demon Deacons, who allowed option-oriented Navy to run for nearly 300 yards, must find a way to contain the Tigers' 'Thunder and Lightning.'When Clemson loses, Davis and Spiller are ineffective - they combined for 20 yards against Alabama and 31 in the second half against Maryland.
Players to watch
Clemson: Spiller has gashed the Demon Deacons with his breakaway speed. He had a 72-yard touchdown run in 2006 and returned a kickoff 90 yards for a score last year.
ong ground game has yet to produce a 100-yard rusher. He's coming off a four-interception game against the Midshipmen.
Clemson is the only team to beat Wake Forest twice during the past two seasons. ... Coach Jim Grobe is one victory shy of 50 with the Demon Deacons. ... Tigers' 56 wins over Wake Forest are its highest total against any ACC opponent. They've beaten only South Carolina (63) more often.

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