CLEVELAND (AP) -Jon Lester, whose rookie season ended suddenly when he was diagnosed with cancer, pitched six innings to win his first game in 11 months, leading Boston to a 6-2 victory over Cleveland on Monday night.
Lester allowed two runs and five hits to easily handle the Indians, the AL's best team at home. The 23-year-old left-hander was diagnosed with anaplastic large cell lymphoma, a highly treatable form of cancer, just days after he improved to 7-2 with a win over the Los Angeles Angels on Aug. 23. He underwent six chemotherapy sessions that eventually eradicated the disease.
Coco Crisp went 4-for-5 and scored three runs for Boston, which jumped to a 5-0 lead in the second off Jake Westbrook (1-6).
Manny Ramirez had two RBIs as the Red Sox (60-39) became the majors' first team to reach 60 wins.
Grady Sizemore hit a two-run homer for the Indians.
Blue Jays 6, Twins 4
TORONTO (AP) - Frank Thomas homered twice to raise his total to 503 and pull within one of Eddie Murray for 20th place as Toronto sent Johan Santana to a rare second-half loss.
Reed Johnson and Alex Rios hit solo shots off Santana (11-8), who allowed four homer in a game for the first time in 163 major league starts. He gave up three homers five times previously. Santana dropped to 41-6 following the All-Star game since the 2003 break. He allowed six runs and seven hits in five innings.
Thomas hit a two-run homer in the second that put the Blue Jays ahead 3-0 and another two-run drive in the fifth that made it 6-3. It was his 30th multihomer game, his first this year.
Justin Morneau hit two home runs for Minnesota, his fifth multihomer game this season, and Torii Hunter also homered.
Shaun Marcum (6-4) allowed four runs and eight hits in six innings.

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