ST. LOUIS (AP) -A 97-yard drive put the New York offense in gear. Another stifling effort from a big-play defense led by Justin Tuck made much of the scoring window dressing in the Giants' 12th straight away win, including their Super Bowl victory last February.
Eli Manning threw three touchdown passes and the Giants sacked Marc Bulger six times while limiting the St. Louis Rams to a fluke touchdown in a 41-13 victory on Sunday. The Rams (0-2) came up with another dud in their home opener, which also served as a tribute to late owner Georgia Frontiere.
The Giants (2-0) have not lost a road game since their opener last season.
Tuck's 41-yard interception return in the fourth quarter sealed the victory, and he added a pair of sacks. Fred Robbins also had two sacks for the Giants.
Manning was 20-for-29 for 260 yards, including hitting Plaxico Burress on a 33-yard TD strike in the first quarter, Brandon Jacobs had 93 yards on 15 carries and 44-year-old kicker John Carney added field goals of 39 and 33 yards in the first half.
MINNEAPOLIS (AP) - Taking a beating all afternoon, Peyton Manning peeled himself off the Metrodome turf and gave it right back to the Minnesota defense.
Manning rallied Indianapolis from a 15-0 hole late in the third quarter, moving Adam Vinatieri into position for the winning field goal with 3 seconds left.
Avoiding his first 0-2 start since his rookie season in 1998, Manning zinged a 20-yard pass on third-and-9 to Reggie Wayne up the seam before Vinatieri - who uncharacteristically missed a 30-yarder earlier - made his 47-yard kick.
Minnesota (0-2) wasted yet another strong effort by a dominant defense, failing again to figure out that pesky old forward pass.
Manning definitely has it down, though he hasn't looked his usual sharp self this September following summer knee surgery. He finished 26-for-42 for 311 yards, one touchdown and two interceptions, but those numbers belied the story of the first three quarters.
Adrian Peterson rushed for 118 of his 160 yards in the first half, and the Vikings were in the Colts' half of the field on their first eight possessions - coming away with five field goals by Ryan Longwell.
Packers 48, Lions 25
DETROIT (AP) - Aaron Rodgers threw three touchdown passes in the first four drives of his second start, helping Green Bay build a big lead it needed.
int with 7:41 left after Calvin Johnson caught his second TD in the fourth quarter.
The Packers (2-0) went back ahead with a field goal on the ensuing drive, then turned the game into the rout it had been for much of the day with three straight interceptions.
Charles Woodson and Nick Collins returned two of the picks for touchdowns, giving Green Bay a lopsided lead again.
Rodgers was 24-of-38 for 328 yards, three scores and a fumble. He threw a TD and ran for another in his debut as an NFL starter, leading the Packers over the Vikings.
Brandon Jackson ran for 61 yards, including a 19-yard score that put the Packers ahead by more than a TD with 3 1/2 minutes left. Greg Jennings caught six passes for 167 yards, while Donald Driver, James Jones and Jordy Nelson all had TD receptions.
The Lions are 0-2 for the fifth time since 2001.
Raiders 23, Chiefs 8
KANSAS CITY, Mo. (AP) - The Raiders, with plenty of help from Kansas City, set aside all their backbiting and turmoil long enough to win a football game.
Rookie Darren McFadden ran for 164 yards and a touchdown and Sebastian Janikowski kicked a team-record 56-yard field goal against an inept Chiefs team that tried three quarterbacks.
Lane Kiffin, amid reports that his job is in jeopardy, won for just the fifth time 18 games as coach of the Raiders (1-1).
90 by Michael Bush, who all by himself beat the Chiefs' 55 yards on the ground. Kansas City started 0-2 for the third time in three years under Herm Edwards and has lost 11 regular-season games in a row.
In using three quarterbacks, the Chiefs had only 65 net yards at halftime and barely managed to avoid their first home shutout since 1994.
Titans 24, Bengals 7
CINCINNATI (AP) - With Vince Young not even with the team, the Titans ended a troubling and confusing week by winning in a breeze.
Backup quarterback Kerry Collins threw low, tight passes that stayed on track in Cincinnati's wind-tunnel of a stadium. Collins threw his first touchdown pass in two years, rookie Chris Johnson ran for 109 yards, and Rob Bironas guided a low, curving kick between gyrating uprights for a 34-yard field goal. Linebacker Keith Bulluck provided the clincher, blocking Kyle Larson's punt in the end zone with his right arm, then snatching the ball off the ground for another touchdown.
At 2-0, the Titans are off to their best start since 1999, when they won their first three games and made the only Super Bowl appearance in franchise history. It hasn't come easy.
Young sprained his left knee during an opening win over Jacksonville, and the Titans asked police to look for him a day later out of concern for his mental state. The drama consumed their week, and Young didn't accompany the team to Cincinnati.
Collins threw an 11-yard touchdown pass to Justin Gage and made no mistakes against the Bengals (0-2), off to their worst start since Marvin Lewis became head coach in 2003.
Bills 20, Jaguars 16
JACKSONVILLE, Fla. (AP) - Trent Edwards was good early and even better late, doing just enough to lead the Bills (2-0) to their best start in five years.
Edwards completed his first 10 attempts and threw a perfect touchdown pass to James Hardy late in the fourth quarter. Edwards finished 20-of-25 for 239 yards, Marshawn Lynch ran for 59 yards and a score, and Buffalo's defense held Jacksonville in check most of the day. The Jaguars (0-2) are off to their worst start since 2003. They finished 5-11 that season - and could be in for another long one this time around.
Jacksonville took the second-half kickoff and drove 74 yards for a touchdown that tied the score at 10. Maurice Jones-Drew plunged in from 2 yards, then the Jaguars recovered an onside kick that led to a field goal and their first lead in two games this season.
Edwards fumbled on the ensuing possession and Jacksonville tacked on a field goal that made it 16-10.
d zone for a 7-yard score.
Panthers 20, Bears 17
CHARLOTTE, N.C (AP) - After watching the Bears build a big lead behind a stout defense and a rookie running back, the Panthers used the same combination to stage a late comeback for an unlikely 2-0 start.
Jonathan Stewart rushed for all but one of his 77 yards in the second half and scored two touchdowns, including the go-ahead TD late in the fourth quarter, and the Panthers stopped the Bears (1-1) on fourth-and-1 with under 2 minutes left.
The Panthers scored the game's final 17 points, recovering from a mistake-prone first half, behind their improved defense.
Chris Harris' forced fumble against his former team set up a touchdown, and Jake Delhomme engineered his second straight fourth-quarter comeback following his return from elbow surgery.
Without suspended star receiver Steve Smith, the Panthers snapped a four-game losing streak in home openers, a week after they stunned San Diego with a touchdown on the final play.
Redskins 29, Saints 24
LANDOVER, Md. (AP) - Jason Campbell hit Santana Moss for a 67-yard touchdown pass that won the game. Campbell and new Washington Redskins coach Jim Zorn's West Coast offense succeeded in Week 2 as spectacularly as it failed in Week 1. Campbell went from uncomfortable to prolific, completing 24 of 36 passes for 321 yards.
ush, stepped forward and hit Moss in stride, the receiver one step ahead of cornerback Tracy Porter. The completion was the longest of Campbell's career. Moss finished with seven catches for 164 yards for the Redskins (1-1).
Seventh-round draft pick Chris Horton, making his first NFL start because of Reed Doughty's illness, was in the right place at the right time with two interceptions off tipped balls and a fumble recovery - accounting for all three turnovers for the Sains (1-1).
New Orleans' Reggie Bush returned a punt 55 yards for a touchdown.

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