Patriots vs. Colts Week 15 Prediction

Patriots vs. Colts, 12/18/21 NFL Week 15 Betting Predictions & Odds

The lone NFL game on Saturday night will take place at Lucas Oil Stadium in Indianapolis, IN where the Colts will host the Patriots at 8:15 p.m. ET. Will the Patriots cover as a 2.5-point underdog or is there a better bet for this Week 15 NFL matchup?

Game Snapshot

311 New England Patriots (+2.5) at 312 Indianapolis Colts (-2.5); o/u 45

8:15 p.m. ET, Saturday, December 18, 2021

Lucas Oil Stadium, Indianapolis, IN

TV: NFL Network

New England Patriots DFS Spin

Rhamondre Stevenson is in line to start in Week 15 against the Colts. When Harris missed Week 10 with a concussion, Stevenson handled 24 touches and totaled 114 yards and two touchdowns. The Colts have played well against the run this season, and Stevenson could be bottled up, even with a full workload. However, Stevenson ranks RB12 in NFL Next Gen's success per attempt metric and fourth in Pro Football Focus' elusive rating. He looks capable of ripping off consistent chunk gains even in a difficult matchup. Stevenson profiles as low-end RB1.

Indianapolis Colts DFS Spin

Colts C Ryan Kelly has been ruled out for Week 15 against the Patriots. Kelly spent 10 days on the reserve/COVID list but returned to practice this week. His Week 15 absence is due to a personal matter. With Kelly out, Danny Pinter will start at center for the Colts.

NFL Week 15 Betting Prediction

The Patriots are 5-1 against the spread in their last six games against the Colts, are 7-0 against the number in their last seven games overall and are 5-0 at the betting window in their last five conference games. On the other side, the Colts are just 3-7 against the spread in their last 10 home games, are 4-10 at the betting window in their last 14 games after allowing less than 90 yards rushing in their previous game and are 2-5 against the spread in their last seven games as a home favorite.

NFL WEEK 15 PREDICTION: NEW ENGLAND PATRIOTS +2.5

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