NFL Week 15 Opening Point Spreads

NFL Week 15 Opening Point Spread Odds & Over/Under Totals

Despite suffering significant injuries on offense in Week 14, both the Panthers and Bengals opened as road favorites in Week 15.

View NFL Week 15 Odds

Panthers at Giants, 1:00PM ET, Sunday

The undefeated Panthers lambasted NFC South rivals the Falcons 38-0 on Sunday and have opened as road favorites versus the Giants in Week 15 despite Jonathan Stewart and Greg Olsen both suffering injuries. Stewart should be fine despite suffering a foot injury in the win over Atlanta, while Olsen should also be good to go after sitting out Sunday's second half with a knee injury. According to oddsmakers from online sports book Mybookie.ag, the Panthers have opened as 5.5-point favorites at the Giants on Sunday.

Bengals at 49ers, 4:25PM ET, Sunday

While Olsen and Stewart should be fine for the Panthers, the Bengals will defintiely be without quarterback Andy Dalton for the foreseeable future. Dalton suffered a fractured thumb in the team's loss to the Steelers in Week 14 and will likely miss the rest of the regular season. Despite going from Dalton to second-year backup A.J. McCarron, Cincinnati still opened as a 4-point road favorite for Sunday's game in San Francisco.

Broncos at Steelers, 4:25PM ET, Sunday

Even though Brock Osweiler played poorly in the Broncos' home loss to the Raiders on Sunday and the Steelers have looked great in back-to-back weeks, it's still a little surprising to see Pittsburgh open as a 6-point favorite over Denver in Week 15. This matchup could be a potential playoff preview because if the postseason were to start today, Denver would be the three-seed in the AFC while Pittsburgh would be the six-seed. That means the Steelers would travel to Denver to take on the Broncos in the wild card round of the playoffs. We'll see if sharp bettors take the points with a Broncos team that continues to play well defensively.

NFL Week 15 Point Spreads

301 Tampa Bay Buccaneers PK (41)

302 St. Louis Rams PK

303 New York Jets -3 (42.5)

304 Dallas Cowboys +3

305 Chicago Bears +5 (43)

306 Minnesota Vikings -5

307 Atlanta Falcons +3 (48.5)

308 Jacksonville Jaguars -3

309 Houston Texans N/A

310 Indianapolis Colts N/A

311 Kansas City Chiefs -7 (43)

312 Baltimore Ravens +7

313 Buffalo Bills PK (44)

314 Washington Redskins PK

315 Tennessee Titans +13.5

316 New England Patriots -13.5

317 Arizona Cardinals -3.5 (50.5)

318 Philadelphia Eagles +3.5

319 Carolina Panthers -5.5

320 New York Giants +5.5

321 Cleveland Browns +14.5 (43)

322 Seattle Seahawks -14.5

323 Green Bay packers -3 (46.5)

324 Oakland Raiders +3

325 Miami Dolphins +1

326 San Diego Chargers -1

327 Denver Broncos +6 (45)

328 Pittsburgh Steelers -6

329 Cincinnati Bengals -4 (42)

330 San Francisco 49ers +4

331 Detroit Lions +3 (50.5)

332 New Orleans Saints -3

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