Bills vs. Rams Pick

Bills vs. Rams NFL Week 5 Picks - Will it be a defensive struggle in L.A.?

The Bills and Rams will square off in Los Angeles this Sunday in what should be a defensive struggle at 4:25PM ET.

According to oddsmakers from online sports book BetDSI, the Rams are 2-point home favorites versus the Bills after opening as a 2.5-point favorite. As for the total, the number opened at 40 and has been bet down to 39.5 at the majority of sports books.

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The Bills are coming off back-to-back wins over the Cardinals (33-18 at home) and the Patriots (16-0 in New England) to get to 2-2 on the year. They're also 2-2 against the spread after covering in back-to-back games as an underdog. Quarterback Tyrod Taylor completed 27-of-39 passes for 246 yards and a touchdown in the win, while LeSean McCoy rushed 19 times for 70 yards.

The Rams have shockingly won three straight games to get to 3-1 on the season and 3-1 against the spread. In their 17-13 win over the Cardinals last week in Arizona, Case Keenum completed 18-of-30 passes for 266 yards with two touchdowns and no picks, while Brian Quick caught both of the quarterback's touchdown passes. The Rams' defense also forced four turnovers and nearly had another interception late but cornerback Trumaine Johnson couldn't get a second foot down along the sidelines after getting his hands on a Carson Palmer pass.

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OUR PICK: The under is a perfect 5-0 in the Bills' last five games coming off a win and is 5-2 in their last seven road games. On the other side, the under is 16-5 in the Rams' last 21 games and is 9-2 in their last 11 games coming off a victory. Neither of these teams figure to score much and while the over is 4-1 in the last five meetings between these two teams, it's hard to fathom this game turning into a shootout.



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