Seahawks vs. 49ers Week 4 Prediction

Seahawks vs. 49ers, 10/3/21 NFL Week 4 Betting Predictions

NFC West rivals clash in Santa Clara on Sunday when the 49ers host the Seahawks at 4:05 p.m. ET. Which of these teams coming off a loss in Week 3 will rebound in Week 4?

Game Snapshot

271 Seattle Seahawks (+2.5) at 272 San Francisco 49ers (-2.5); o/u 52

4:05 p.m. ET, Sunday, October 3, 2021

NFL Week 4 Regular Season

Seattle Seahawks DFS Spin

ESPN's Adam Schefter reports Tyler Lockett (hip) is expected to play in Week 4 against the 49ers. Lockett practiced Friday after being downgraded to a DNP on Thursday. The veteran receiver has a history of posting middling fantasy numbers while playing through injuries but it's impossible to bench a receiver who has seen 20 targets from Russell Wilson through three games. Lockett is a risky fantasy option but his ceiling is worth chasing as a WR2.

San Francisco 49ers DFS Spin

George Kittle (calf) is questionable for Week 4 against the Seahawks. Coach Kyle Shanahan said the team will have a "good idea" by tomorrow whether Kittle can play, though they're at least encouraged at this time that he was able to participate in some capacity on Friday. Ross Dwelley, who averaged two targets per game across nine starts last year, would replace Kittle off the bench if the latter is ruled out.

Seahawks vs. 49ers Betting Prediction

The Seahawks are 13-5-1 against the spread in their last 19 games versus the 49ers, are 11-4 against the number in their last 15 games as an underdog and are 32-15-4 against the spread in their last 51 games following a loss. On the other side, the 49ers are 1-4 against the spread in their last five home games, are 10-26-1 against the number in their last 37 games as a favorite and are 5-21-1 at the betting window in their last 27 games as a home favorite.

NFL WEEK 4 BETTING PREDICTION: SEATTLE SEAHAWKS +2.5

Recent NFL Discussions

Newsletters for February 2023 on Fri, Feb 2023 by Shazman
PEBBLE BEACH PRO AM ROUNDS 1TO 4 on Fri, Feb 2023 by Timmy1961
COLL PRO HOOPS FOR THURS on Thu, Feb 2023 by Timmy1961

NFL Predictions & Picks

Thumbnail Best NFL Players Not in the Hall of Fame Not so long ago, the NFL Hall of Fame was replenished with eight more names of the best football players of all time.
Thumbnail 49ers vs. Eagles Prediction & Odds The Eagles will be slight favorites when they host the 49ers in the NFC Championship Game on Sunday at 3:00 p.m. ET. Even with a rookie under center, is San...
Thumbnail NFC Championship Game Total Prediction The total for Sunday’s NFC Championship Game between the 49ers and Eagles opened at 45.5 but has been bet up to 46.5.
Thumbnail Bengals vs. Chiefs Prediction & Odds Patrick Mahomes will suit up for the Chiefs when they host the Bengals as 1.5-point home favorites in Sunday’s AFC Championship Game at 6:30 p.m. ET.
Thumbnail AFC Championship Game Total Prediction With Patrick Mahomes set to play the AFC Championship Game despite suffering a high ankle sprain in last week’s win over the Jaguars, many believe that the...

NFL Headlines