Cardinals vs. Rams NFL Week 4 Prediction

Cardinals vs. Rams, 10/3/21 NFL Week 4 Betting Predictions

It’ll be a battle of unbeaten rivals from the NFC West when the Rams host the Cardinals at 4:05 p.m. ET on Sunday. With the Rams laying 4.5 points and the total sitting at 54.5, what’s the best play for this matchup?

Game Snapshot

269 Arizona Cardinals (+4.5) at 270 Los Angeles Rams (-4.5); o/u 54.5

4:05 p.m. ET, Sunday, October 3, 2021

NFL Week 4 Regular Season

Arizona Cardinals DFS Spin

Kyler Murray completed 28-of-34 passes for 316 scoreless yards and one interception in the Cardinals' 31-19, Week 3 win over the Jaguars, adding seven carries for 19 rushing yards and one touchdown. The Cardinals did all of their scoring via three rushing touchdowns, the first coming from Murray on a play-action boot from one yard out in the first quarter to get the scoring started. James Conner then rushed for a pair of inside-the-five touchdowns in the second half. With DeAndre Hopkins (ribs) playing at less than 100%, A.J. Green (5-112) and Christian Kirk (7-104) both went over 100 yards. Murray gets a tough Week 4 draw with the Rams but remains an obvious high-end QB1 no matter the matchup.

Los Angeles Rams DFS Spin

Matthew Stafford completed 27-of-38 passes for 373 yards and four touchdowns in the Rams' Week 3 win against the Bucs. Stafford tormented a Tampa secondary that had allowed a 72 percent completion rate headed into Week 3, picking them apart underneath with Cooper Kupp and Tyler Higbee, and over the top with DeSean Jackson. The Rams' passing attack was unstoppable on a day where they didn't even pretend to establish the run against the fearsome Tampa front four. Stafford looks like the final piece in Sean McVay's progressive, efficient offensive system. He should be considered a top-5 option in Week 4 against Arizona in what shapes up as a high-scoring affair.

Cowboys vs. Bucs Betting Prediction

The Cardinals are 0-3-1 against the spread in their last four road games against L.A. and are 0-7-1 against the number in their last eight games versus the Rams overall. The favorite is also 9-1-1 against the spread in the last 11 meetings between these two teams, while the Rams are 4-1 ATS in their last five home games. L.A. is 23-8-1 against the number in its last 32 games versus conference opponents and is 10-4-1 ATS in its last 15 divisional games as well.

NFL WEEK 4 BETTING PREDICTION: LOS ANGELS RAMS -4.5

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